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WRN WRN RecQ like helicase [ Saimiri boliviensis (Bolivian squirrel monkey) ]

Gene ID: 101048471, updated on 8-Mar-2024

Summary

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Gene symbol
WRN
Gene description
WRN RecQ like helicase
See related
EnsemblRapid:ENSSBOG00000027238
Gene type
protein coding
RefSeq status
MODEL
Organism
Saimiri boliviensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Saimiriinae; Saimiri
Orthologs
human mouse all
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Genomic context

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See WRN in Genome Data Viewer
Location:
chromosome: Un
Exon count:
34
Annotation release Status Assembly Chr Location
102 current BCM_Sbol_2.0 (GCF_016699345.1) Unplaced Scaffold NW_024100955.1 (11663025..11787961, complement)

NW_024100955.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L6-like Neighboring gene lysophosphatidic acid receptor 1-like Neighboring gene acyl-CoA:lysophosphatidylglycerol acyltransferase 1-like Neighboring gene purine rich element binding protein G

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_024100955 Unplaced Scaffold Reference BCM_Sbol_2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3'-5' DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 3'-5' exonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables four-way junction helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA unwinding involved in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in G-quadruplex DNA unwinding IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in telomere maintenance IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
Werner syndrome ATP-dependent helicase
Names
Werner syndrome RecQ like helicase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Saimiri boliviensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BCM_Sbol_2.0 Primary Assembly

Genomic

  1. NW_024100955.1 Reference BCM_Sbol_2.0 Primary Assembly

    Range
    11663025..11787961 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010348683.2 → XP_010346985.2  Werner syndrome ATP-dependent helicase

    UniProtKB/TrEMBL
    A0A2K6TP36
    Related
    ENSSBOP00000021357.2, ENSSBOT00000038193.2
    Conserved Domains (4) summary
    smart00341
    Location:1149 → 1227
    HRDC; Helicase and RNase D C-terminal
    TIGR00614
    Location:536 → 1009
    recQ_fam; ATP-dependent DNA helicase, RecQ family
    cd06129
    Location:61 → 229
    RNaseD_like; DEDDy 3'-5' exonuclease domain of RNase D, WRN, and similar proteins
    pfam14493
    Location:1256 → 1350
    HTH_40; Helix-turn-helix domain
Nucleotide Protein
Heading Accession and Version

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