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HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 [ Papio anubis (olive baboon) ]

Gene ID: 101022372, updated on 8-Mar-2024

Summary

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Gene symbol
HMGCS2
Gene description
3-hydroxy-3-methylglutaryl-CoA synthase 2
See related
Ensembl:ENSPANG00000011380
Gene type
protein coding
RefSeq status
MODEL
Organism
Papio anubis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Papio
Orthologs
human mouse all
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Genomic context

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See HMGCS2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
10
Annotation release Status Assembly Chr Location
104 current Panubis1.0 (GCF_008728515.1) 1 NC_044976.1 (117979346..118001155, complement)
103 previous assembly Panu_3.0 (GCF_000264685.3) 1 NC_018152.2 (117031327..117053719, complement)

Chromosome 1 - NC_044976.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 697 Neighboring gene phosphoglycerate dehydrogenase Neighboring gene regenerating family member 4 Neighboring gene uncharacterized LOC110740756

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxymethylglutaryl-CoA synthase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Papio anubis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Panubis1.0 Primary Assembly

Genomic

  1. NC_044976.1 Reference Panubis1.0 Primary Assembly

    Range
    117979346..118001155 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009216758.2 → XP_009215022.1  hydroxymethylglutaryl-CoA synthase, mitochondrial

    See identical proteins and their annotated locations for XP_009215022.1

    UniProtKB/TrEMBL
    A0A096N5K0, A0A2I3MPQ2
    Conserved Domains (3) summary
    TIGR01833
    Location:50 → 506
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
    pfam01154
    Location:53 → 223
    HMG_CoA_synt_N; Hydroxymethylglutaryl-coenzyme A synthase N terminal
    pfam08540
    Location:224 → 506
    HMG_CoA_synt_C; Hydroxymethylglutaryl-coenzyme A synthase C terminal

  2. XM_003892497.3 → XP_003892546.1  hydroxymethylglutaryl-CoA synthase, mitochondrial

    See identical proteins and their annotated locations for XP_003892546.1

    UniProtKB/TrEMBL
    A0A096N5K0, A0A2I3MPQ2
    Related
    ENSPANP00000007713.1, ENSPANT00000020507.3
    Conserved Domains (3) summary
    TIGR01833
    Location:50 → 506
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
    pfam01154
    Location:53 → 223
    HMG_CoA_synt_N; Hydroxymethylglutaryl-coenzyme A synthase N terminal
    pfam08540
    Location:224 → 506
    HMG_CoA_synt_C; Hydroxymethylglutaryl-coenzyme A synthase C terminal
Nucleotide Protein
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