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PLCB2 phospholipase C beta 2 [ Papio anubis (olive baboon) ]

Gene ID: 101010000, updated on 8-Mar-2024

Summary

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Gene symbol
PLCB2
Gene description
phospholipase C beta 2
See related
Ensembl:ENSPANG00000019485
Gene type
protein coding
RefSeq status
MODEL
Organism
Papio anubis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Papio
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
34
Annotation release Status Assembly Chr Location
104 current Panubis1.0 (GCF_008728515.1) 7 NC_044982.1 (146723566..146743655)
103 previous assembly Panu_3.0 (GCF_000264685.3) 7 NC_018158.2 (14867532..14889267, complement)

Chromosome 7 - NC_044982.1Genomic Context describing neighboring genes Neighboring gene 60S acidic ribosomal protein P0 pseudogene Neighboring gene InaF motif containing 2 Neighboring gene ankyrin repeat domain 63 Neighboring gene p21 (RAC1) activated kinase 6 Neighboring gene uncharacterized LOC103885760

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Papio anubis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Panubis1.0 Primary Assembly

Genomic

  1. NC_044982.1 Reference Panubis1.0 Primary Assembly

    Range
    146723566..146743655
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031668838.1 → XP_031524698.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1

    Conserved Domains (5) summary
    cd00275
    Location:681 → 802
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:311 → 649
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    cd16209
    Location:149 → 299
    EFh_PI-PLCbeta2; EF-hand motif found in phosphoinositide phospholipase C beta 2 (PI-PLC-beta2)
    pfam08703
    Location:979 → 1160
    PLC-beta_C; PLC-beta C terminal
    pfam17787
    Location:13 → 141
    PH_14; PH domain

  2. XM_003900764.4 → XP_003900813.2  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X4

    UniProtKB/TrEMBL
    A0A2I3LTM1
    Related
    ENSPANP00000026787.2, ENSPANT00000052712.2
    Conserved Domains (5) summary
    cd00275
    Location:681 → 802
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:311 → 649
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    cd16209
    Location:149 → 299
    EFh_PI-PLCbeta2; EF-hand motif found in phosphoinositide phospholipase C beta 2 (PI-PLC-beta2)
    pfam08703
    Location:979 → 1153
    PLC-beta_C; PLC-beta C terminal
    pfam17787
    Location:13 → 141
    PH_14; PH domain

  3. XM_031668839.1 → XP_031524699.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X2

    Conserved Domains (6) summary
    cd00275
    Location:681 → 802
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:311 → 649
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    COG5281
    Location:807 → 1145
    COG5281; Phage-related minor tail protein [Mobilome: prophages, transposons]
    cd16209
    Location:149 → 299
    EFh_PI-PLCbeta2; EF-hand motif found in phosphoinositide phospholipase C beta 2 (PI-PLC-beta2)
    pfam08703
    Location:978 → 1159
    PLC-beta_C; PLC-beta C terminal
    pfam17787
    Location:13 → 141
    PH_14; PH domain

  4. XM_031668842.1 → XP_031524702.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X6

    Conserved Domains (5) summary
    cd00275
    Location:681 → 802
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:311 → 649
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    cd16209
    Location:149 → 299
    EFh_PI-PLCbeta2; EF-hand motif found in phosphoinositide phospholipase C beta 2 (PI-PLC-beta2)
    pfam08703
    Location:964 → 1145
    PLC-beta_C; PLC-beta C terminal
    pfam17787
    Location:13 → 141
    PH_14; PH domain

  5. XM_003900765.4 → XP_003900814.2  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X7

    UniProtKB/TrEMBL
    A0A2I3MHL6
    Related
    ENSPANP00000035287.2, ENSPANT00000046148.2
    Conserved Domains (6) summary
    cd00275
    Location:681 → 802
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:311 → 649
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    COG5281
    Location:807 → 1111
    COG5281; Phage-related minor tail protein [Mobilome: prophages, transposons]
    cd16209
    Location:149 → 299
    EFh_PI-PLCbeta2; EF-hand motif found in phosphoinositide phospholipase C beta 2 (PI-PLC-beta2)
    pfam08703
    Location:964 → 1138
    PLC-beta_C; PLC-beta C terminal
    pfam17787
    Location:13 → 141
    PH_14; PH domain

  6. XM_031668840.1 → XP_031524700.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X3

    Conserved Domains (5) summary
    cd00275
    Location:677 → 798
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:311 → 645
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    cd16209
    Location:149 → 299
    EFh_PI-PLCbeta2; EF-hand motif found in phosphoinositide phospholipase C beta 2 (PI-PLC-beta2)
    pfam08703
    Location:975 → 1156
    PLC-beta_C; PLC-beta C terminal
    pfam17787
    Location:13 → 141
    PH_14; PH domain

  7. XM_009209917.3 → XP_009208181.2  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X5

    Conserved Domains (5) summary
    cd00275
    Location:677 → 798
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:311 → 645
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    cd16209
    Location:149 → 299
    EFh_PI-PLCbeta2; EF-hand motif found in phosphoinositide phospholipase C beta 2 (PI-PLC-beta2)
    pfam08703
    Location:975 → 1149
    PLC-beta_C; PLC-beta C terminal
    pfam17787
    Location:13 → 141
    PH_14; PH domain

  8. XM_021940418.2 → XP_021796110.2  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X8

    Conserved Domains (5) summary
    cd00275
    Location:681 → 802
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:311 → 649
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    cd16209
    Location:149 → 299
    EFh_PI-PLCbeta2; EF-hand motif found in phosphoinositide phospholipase C beta 2 (PI-PLC-beta2)
    pfam08703
    Location:979 → 1118
    PLC-beta_C; PLC-beta C terminal
    pfam17787
    Location:13 → 141
    PH_14; PH domain

  9. XM_031668845.1 → XP_031524705.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X11

    Conserved Domains (4) summary
    cd00275
    Location:681 → 802
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:311 → 649
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    cd16209
    Location:149 → 299
    EFh_PI-PLCbeta2; EF-hand motif found in phosphoinositide phospholipase C beta 2 (PI-PLC-beta2)
    pfam17787
    Location:13 → 141
    PH_14; PH domain

  10. XM_031668846.1 → XP_031524706.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X12

    Conserved Domains (4) summary
    cd00275
    Location:681 → 802
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:311 → 649
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    cd16209
    Location:149 → 299
    EFh_PI-PLCbeta2; EF-hand motif found in phosphoinositide phospholipase C beta 2 (PI-PLC-beta2)
    pfam17787
    Location:13 → 141
    PH_14; PH domain

  11. XM_017960519.3 → XP_017816008.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X13

    Related
    ENSPANP00000036598.1, ENSPANT00000039600.2
    Conserved Domains (3) summary
    cd15898
    Location:149 → 178
    EFh_PI-PLC; EF-hand motif [structural motif]
    cl28895
    Location:149 → 194
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    pfam17787
    Location:13 → 141
    PH_14; PH domain

  12. XM_031668843.1 → XP_031524703.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X9

    Conserved Domains (5) summary
    cd00275
    Location:626 → 747
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:256 → 594
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    cd16209
    Location:94 → 244
    EFh_PI-PLCbeta2; EF-hand motif found in phosphoinositide phospholipase C beta 2 (PI-PLC-beta2)
    pfam08703
    Location:924 → 1105
    PLC-beta_C; PLC-beta C terminal
    pfam17787
    Location:1 → 86
    PH_14; PH domain

  13. XM_031668844.1 → XP_031524704.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X10

    Conserved Domains (5) summary
    cd00275
    Location:493 → 614
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:123 → 461
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    cd15898
    Location:32 → 61
    EFh_PI-PLC; EF-hand motif [structural motif]
    cl28895
    Location:7 → 111
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    pfam08703
    Location:791 → 972
    PLC-beta_C; PLC-beta C terminal

RNA

  1. XR_004185192.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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