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PFKL phosphofructokinase, liver type [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100993510, updated on 10-Oct-2024

Summary

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Gene symbol
PFKL
Gene description
phosphofructokinase, liver type
See related
Ensembl:ENSPPAG00000028154
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See PFKL in Genome Data Viewer
Location:
chromosome: 22
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 22 NC_073271.2 (40307925..40334593)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 21 NC_073270.1 (35158060..35184538)

Chromosome 22 - NC_073271.2Genomic Context describing neighboring genes Neighboring gene DNA methyltransferase 3 like Neighboring gene autoimmune regulator Neighboring gene uncharacterized LOC129394974 Neighboring gene cilia and flagella associated protein 410 Neighboring gene transient receptor potential cation channel subfamily M member 2 Neighboring gene uncharacterized LOC130541124

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructokinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables AMP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-6-phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables identical protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables monosaccharide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical glycolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose 1,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose 6-phosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of 6-phosphofructokinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ATP-dependent 6-phosphofructokinase, liver type

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073271.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    40307925..40334593
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034948083.3 → XP_034803974.1  ATP-dependent 6-phosphofructokinase, liver type isoform X1

    UniProtKB/TrEMBL
    A0A2R9A1U1
    Conserved Domains (1) summary
    cd00764
    Location:13 → 773
    Eukaryotic_PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent ...

  2. XM_055105298.2 → XP_054961273.1  ATP-dependent 6-phosphofructokinase, liver type isoform X3

  3. XM_055105297.2 → XP_054961272.1  ATP-dependent 6-phosphofructokinase, liver type isoform X2

    UniProtKB/TrEMBL
    A0A2R8ZY35
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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