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VCAN versican [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100993269, updated on 8-Mar-2024

Summary

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Gene symbol
VCAN
Gene description
versican
See related
Ensembl:ENSPPAG00000026050
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See VCAN in Genome Data Viewer
Location:
chromosome: 4
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 4 NC_073253.2 (31721703..31832599, complement)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 5 NC_073254.1 (29875328..29986197, complement)

Chromosome 4 - NC_073253.2Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene hyaluronan and proteoglycan link protein 1 Neighboring gene tubulin beta-8 chain-like Neighboring gene coenzyme Q-binding protein COQ10 homolog B, mitochondrial-like Neighboring gene X-ray repair cross complementing 4 Neighboring gene small nucleolar RNA U109 Neighboring gene transmembrane protein 167A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hyaluronic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in central nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glial cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of neuroblast proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in skeletal system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in perineuronal net IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
versican core protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073253.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    31721703..31832599 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008975779.6 → XP_008974027.2  versican core protein isoform X2

    UniProtKB/TrEMBL
    A0A2R8ZPX8
    Conserved Domains (6) summary
    cd00033
    Location:2309 → 2365
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    cd03588
    Location:2182 → 2305
    CLECT_CSPGs; C-type lectin-like domain (CTLD) of the type found in chondroitin sulfate proteoglycan core proteins
    cd00054
    Location:2140 → 2176
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd03517
    Location:150 → 244
    Link_domain_CSPGs_modules_1_3; this extracellular link domain is found in the first and third link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan. In addition, it is found in the first link module of three other CSPGs: versican, neurocan, and brevican. ...
    cd03520
    Location:251 → 346
    Link_domain_CSPGs_modules_2_4; this link domain is found in the second and fourth link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan and, in the second link module of three other CSPGs: versican, neurocan, and brevican. The link domain is a hyaluronan ...
    cd05901
    Location:26 → 152
    Ig_Versican; Immunoglobulin (Ig)-like domain of the chondroitin sulfate proteoglycan core protein (CSPG), versican

  2. XM_034959843.3 → XP_034815734.1  versican core protein isoform X3

    UniProtKB/TrEMBL
    A0A2R8ZVS3
    Conserved Domains (6) summary
    cd00033
    Location:1542 → 1598
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    cd03588
    Location:1415 → 1538
    CLECT_CSPGs; C-type lectin-like domain (CTLD) of the type found in chondroitin sulfate proteoglycan core proteins
    cd00054
    Location:1373 → 1409
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd03517
    Location:150 → 244
    Link_domain_CSPGs_modules_1_3; this extracellular link domain is found in the first and third link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan. In addition, it is found in the first link module of three other CSPGs: versican, neurocan, and brevican. ...
    cd03520
    Location:251 → 346
    Link_domain_CSPGs_modules_2_4; this link domain is found in the second and fourth link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan and, in the second link module of three other CSPGs: versican, neurocan, and brevican. The link domain is a hyaluronan ...
    cd05901
    Location:26 → 152
    Ig_Versican; Immunoglobulin (Ig)-like domain of the chondroitin sulfate proteoglycan core protein (CSPG), versican

  3. XM_003822244.5 → XP_003822292.2  versican core protein isoform X1

    UniProtKB/TrEMBL
    A0A2R8ZPY0
    Conserved Domains (6) summary
    cd00033
    Location:3296 → 3352
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    cd03588
    Location:3169 → 3292
    CLECT_CSPGs; C-type lectin-like domain (CTLD) of the type found in chondroitin sulfate proteoglycan core proteins
    cd00054
    Location:3127 → 3163
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd03517
    Location:150 → 244
    Link_domain_CSPGs_modules_1_3; this extracellular link domain is found in the first and third link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan. In addition, it is found in the first link module of three other CSPGs: versican, neurocan, and brevican. ...
    cd03520
    Location:251 → 346
    Link_domain_CSPGs_modules_2_4; this link domain is found in the second and fourth link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan and, in the second link module of three other CSPGs: versican, neurocan, and brevican. The link domain is a hyaluronan ...
    cd05901
    Location:26 → 152
    Ig_Versican; Immunoglobulin (Ig)-like domain of the chondroitin sulfate proteoglycan core protein (CSPG), versican

RNA

  1. XR_008625354.2 RNA Sequence

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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