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NGLY1 N-glycanase 1 [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100990785, updated on 6-Jun-2024

Summary

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Gene symbol
NGLY1
Gene description
N-glycanase 1
See related
Ensembl:ENSPPAG00000043951
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See NGLY1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 2 NC_085926.1 (25678406..25742623, complement)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 3 NC_073252.1 (25683169..25747391, complement)

Chromosome 2 - NC_085926.1Genomic Context describing neighboring genes Neighboring gene DNA topoisomerase II beta Neighboring gene cysteine-rich protein 1-like Neighboring gene large ribosomal subunit protein eL32-like Neighboring gene transcription initiation factor TFIID subunit 9B-like Neighboring gene 3-oxoacyl-ACP synthase, mitochondrial Neighboring gene uncharacterized LOC117979611

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glycoprotein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein deglycosylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein quality control for misfolded or incompletely synthesized proteins IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_085926.1 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    25678406..25742623 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024928238.4 → XP_024784006.2  peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform X1

    UniProtKB/TrEMBL
    A0A2R9CNJ2
    Conserved Domains (4) summary
    cd10459
    Location:19 → 109
    PUB_PNGase; PNGase/UBA or UBX (PUB) domain of the P97 adaptor protein Peptide:N-glycanase (PNGase)
    pfam01841
    Location:275 → 354
    Transglut_core; Transglutaminase-like superfamily
    pfam04721
    Location:457 → 651
    PAW; PNGase C-terminal domain, mannose-binding module PAW
    cl10615
    Location:338 → 392
    sm_acid_XPC-like; small acidic domain of Xeroderma pigmentosum group C complementing protein and similar proteins

  2. XM_008951630.4 → XP_008949878.2  peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform X2

    UniProtKB/TrEMBL
    A0A2R9CNJ2
    Conserved Domains (4) summary
    cd10459
    Location:19 → 109
    PUB_PNGase; PNGase/UBA or UBX (PUB) domain of the P97 adaptor protein Peptide:N-glycanase (PNGase)
    pfam01841
    Location:275 → 354
    Transglut_core; Transglutaminase-like superfamily
    pfam04721
    Location:416 → 596
    PAW; PNGase C-terminal domain, mannose-binding module PAW
    cl10615
    Location:338 → 392
    sm_acid_XPC-like; small acidic domain of Xeroderma pigmentosum group C complementing protein and similar proteins

  3. XM_034955991.3 → XP_034811882.1  peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform X4

    UniProtKB/TrEMBL
    A0A2R9CLE7
    Conserved Domains (3) summary
    cd10459
    Location:19 → 109
    PUB_PNGase; PNGase/UBA or UBX (PUB) domain of the P97 adaptor protein Peptide:N-glycanase (PNGase)
    pfam01841
    Location:275 → 334
    Transglut_core; Transglutaminase-like superfamily
    pfam04721
    Location:439 → 633
    PAW; PNGase C-terminal domain, mannose-binding module PAW

  4. XM_034955992.2 → XP_034811883.1  peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform X5

    UniProtKB/TrEMBL
    A0A2R9CLC9
    Conserved Domains (4) summary
    cd10459
    Location:19 → 109
    PUB_PNGase; PNGase/UBA or UBX (PUB) domain of the P97 adaptor protein Peptide:N-glycanase (PNGase)
    pfam01841
    Location:275 → 354
    Transglut_core; Transglutaminase-like superfamily
    cl10509
    Location:457 → 538
    PAW; PNGase C-terminal domain, mannose-binding module PAW
    cl10615
    Location:338 → 392
    sm_acid_XPC-like; small acidic domain of Xeroderma pigmentosum group C complementing protein and similar proteins

  5. XM_055109572.2 → XP_054965547.1  peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform X3

    UniProtKB/TrEMBL
    A0A2R9CLC9
Nucleotide Protein
Heading Accession and Version

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