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HMGCLL1 3-hydroxy-3-methylglutaryl-CoA lyase like 1 [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100990466, updated on 11-Apr-2024

Summary

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Gene symbol
HMGCLL1
Gene description
3-hydroxy-3-methylglutaryl-CoA lyase like 1
See related
Ensembl:ENSPPAG00000031355
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See HMGCLL1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 5 NC_073254.2 (69896617..70041937, complement)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 6 NC_073255.1 (65773135..65918619, complement)

Chromosome 5 - NC_073254.2Genomic Context describing neighboring genes Neighboring gene hypocretin receptor 2 Neighboring gene GDNF family receptor alpha like Neighboring gene bone morphogenetic protein 5 Neighboring gene nucleophosmin-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA lyase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-leucine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ketone body biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic
Names
3-hydroxymethyl-3-methylglutaryl-CoA lyase L1
3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073254.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    69896617..70041937 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034962260.3 → XP_034818151.1  3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform X2

    UniProtKB/TrEMBL
    A0A2R9ANC4
    Conserved Domains (1) summary
    cl21457
    Location:56 → 366
    TIM; TIM-like beta/alpha barrel domains

  2. XM_003828931.5 → XP_003828979.1  3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform X1

    UniProtKB/TrEMBL
    A0A2R9ALA9, A0A2R9ANC4
    Related
    ENSPPAP00000016455.1
    Conserved Domains (2) summary
    PLN02746
    Location:41 → 336
    PLN02746; hydroxymethylglutaryl-CoA lyase
    pfam00682
    Location:48 → 321
    HMGL-like; HMGL-like
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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