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INPP5D inositol polyphosphate-5-phosphatase D [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100988546, updated on 8-Mar-2024

Summary

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Gene symbol
INPP5D
Gene description
inositol polyphosphate-5-phosphatase D
See related
Ensembl:ENSPPAG00000030895
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See INPP5D in Genome Data Viewer
Location:
chromosome: 13
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 13 NC_073262.2 (135661459..135810426)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 2B NC_073251.1 (135676418..135825387)

Chromosome 13 - NC_073262.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134728778 Neighboring gene neuraminidase 2 Neighboring gene autophagy related 16 like 1 Neighboring gene small Cajal body-specific RNA 6 Neighboring gene small Cajal body-specific RNA 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of bone resorption IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of neutrophil differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of B cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
Names
inositol polyphosphate-5-phosphatase, 145kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073262.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    135661459..135810426
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003813132.4 → XP_003813180.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X2

    Conserved Domains (2) summary
    cd09100
    Location:403 → 709
    INPP5c_SHIP1-INPP5D; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol polyphosphate 5-phosphatase-1 and related proteins
    cd10343
    Location:1 → 102
    SH2_SHIP; Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP)

  2. XM_008965726.4 → XP_008963974.1  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1

    UniProtKB/TrEMBL
    A0A2R9AEZ4
    Related
    ENSPPAP00000015532.1
    Conserved Domains (2) summary
    cd09100
    Location:404 → 710
    INPP5c_SHIP1-INPP5D; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol polyphosphate 5-phosphatase-1 and related proteins
    cd10343
    Location:1 → 102
    SH2_SHIP; Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP)
Nucleotide Protein
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