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PTGIS prostaglandin I2 synthase [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100987973, updated on 17-Aug-2024

Summary

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Official Symbol
PTGIS
Official Full Name
prostaglandin I2 synthase
Primary source
VGNC:VGNC:83065
See related
Ensembl:ENSPPAG00000042097
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See PTGIS in Genome Data Viewer
Location:
chromosome: 21
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 21 NC_073270.2 (55244765..55309216, complement)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 20 NC_073269.1 (55237848..55302529, complement)

Chromosome 21 - NC_073270.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100988300 Neighboring gene small nucleolar SNORD12/SNORD106 Neighboring gene somatomedin-B and thrombospondin type-1 domain-containing protein-like Neighboring gene potassium voltage-gated channel subfamily B member 1 Neighboring gene uncharacterized LOC134729684 Neighboring gene uncharacterized LOC134729667 Neighboring gene beta-1,4-galactosyltransferase 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables prostaglandin-I synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in prostaglandin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
prostacyclin synthase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073270.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    55244765..55309216 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034947711.3 → XP_034803602.1  prostacyclin synthase

    UniProtKB/TrEMBL
    A0A2R9CA03
    Conserved Domains (1) summary
    cd20634
    Location:52 → 493
    PGIS_CYP8A1; prostacyclin Synthase, also called cytochrome P450 family 8, subfamily A, polypeptide 1
Nucleotide Protein
Heading Accession and Version

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