U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PKM pyruvate kinase M1/2 [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100983648, updated on 10-Oct-2024

Summary

Go to the top of the page Help
Gene symbol
PKM
Gene description
pyruvate kinase M1/2
See related
Ensembl:ENSPPAG00000041061
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See PKM in Genome Data Viewer
Location:
chromosome: 16
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 16 NC_073265.2 (61463312..61495601, complement)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 15 NC_073264.1 (65627528..65659784, complement)

Chromosome 16 - NC_073265.2Genomic Context describing neighboring genes Neighboring gene SUMO peptidase family member, NEDD8 specific Neighboring gene GRAM domain containing 2A Neighboring gene poly(ADP-ribose) polymerase family member 6 Neighboring gene hexosaminidase subunit alpha

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyruvate kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
pyruvate kinase PKM
Names
pyruvate kinase, muscle

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073265.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    61463312..61495601 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063596767.1 → XP_063452837.1  pyruvate kinase PKM isoform X11

    UniProtKB/TrEMBL
    A0A2R9CED5

  2. XM_057299900.2 → XP_057155883.1  pyruvate kinase PKM isoform X12

    UniProtKB/TrEMBL
    A0A2R9C418

  3. XM_003818551.6 → XP_003818599.1  pyruvate kinase PKM isoform X11

    See identical proteins and their annotated locations for XP_003818599.1

    UniProtKB/TrEMBL
    A0A2R9C711, A0A2R9CED5
    Related
    ENSPPAP00000036672.1
    Conserved Domains (1) summary
    cd00288
    Location:42 → 530
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...

  4. XM_055098741.2 → XP_054954716.2  pyruvate kinase PKM isoform X8

  5. XM_008971885.7 → XP_008970133.3  pyruvate kinase PKM isoform X7

  6. XM_008971883.5 → XP_008970131.3  pyruvate kinase PKM isoform X2

  7. XM_003818555.7 → XP_003818603.3  pyruvate kinase PKM isoform X1

  8. XM_055098744.2 → XP_054954719.1  pyruvate kinase PKM isoform X11

    UniProtKB/TrEMBL
    A0A2R9CED5

  9. XM_063596768.1 → XP_063452838.1  pyruvate kinase PKM isoform X11

    UniProtKB/TrEMBL
    A0A2R9CED5

  10. XM_055098737.2 → XP_054954712.1  pyruvate kinase PKM isoform X3

  11. XM_055098742.2 → XP_054954717.1  pyruvate kinase PKM isoform X9

  12. XM_055098743.2 → XP_054954718.1  pyruvate kinase PKM isoform X10

  13. XM_055098738.2 → XP_054954713.1  pyruvate kinase PKM isoform X4

  14. XM_055098740.2 → XP_054954715.1  pyruvate kinase PKM isoform X6

  15. XM_055098739.2 → XP_054954714.1  pyruvate kinase PKM isoform X5

  16. XM_008971888.3 → XP_008970136.1  pyruvate kinase PKM isoform X13

    See identical proteins and their annotated locations for XP_008970136.1

    UniProtKB/TrEMBL
    A0A2R9C424, A0A2R9C711
    Related
    ENSPPAP00000036680.1
    Conserved Domains (1) summary
    cd00288
    Location:68 → 515
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.