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HK2 hexokinase 2 [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100983149, updated on 19-Jun-2024

Summary

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Gene symbol
HK2
Gene description
hexokinase 2
See related
Ensembl:ENSPPAG00000038583
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See HK2 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 12 NC_073261.2 (51498596..51561239, complement)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 2A NC_073250.1 (51501345..51563782, complement)

Chromosome 12 - NC_073261.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC130541256 Neighboring gene DNA polymerase epsilon 4, accessory subunit Neighboring gene uncharacterized LOC117979186 Neighboring gene ssemaphorin 4F

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables D-glucose binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructokinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glucokinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glucose 6-phosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glucose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular glucose homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hexokinase-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073261.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    51498596..51561239 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003810321.5 → XP_003810369.1  hexokinase-2 isoform X1

    See identical proteins and their annotated locations for XP_003810369.1

    UniProtKB/TrEMBL
    A0A2R9BNP9, A0A2R9BUJ2
    Related
    ENSPPAP00000031286.1
    Conserved Domains (3) summary
    pfam00349
    Location:471 → 667
    Hexokinase_1; Hexokinase
    pfam03727
    Location:673 → 907
    Hexokinase_2; Hexokinase
    cl27242
    Location:12 → 460
    Hexokinase_2; Hexokinase

  2. XM_008962671.6 → XP_008960919.1  hexokinase-2 isoform X2

    See identical proteins and their annotated locations for XP_008960919.1

    UniProtKB/TrEMBL
    A0A2R9BUJ2
    Conserved Domains (3) summary
    pfam00349
    Location:443 → 639
    Hexokinase_1; Hexokinase
    pfam03727
    Location:645 → 879
    Hexokinase_2; Hexokinase
    cl27242
    Location:1 → 432
    Hexokinase_2; Hexokinase
Nucleotide Protein
Heading Accession and Version

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