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PI4KA phosphatidylinositol 4-kinase alpha [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100980877, updated on 6-Jun-2024

Summary

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Gene symbol
PI4KA
Gene description
phosphatidylinositol 4-kinase alpha
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See PI4KA in Genome Data Viewer
Location:
chromosome: 23
Exon count:
56
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 23 NC_085927.1 (30414241..30565263, complement)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 22 NC_073271.1 (32963144..33114773, complement)

Chromosome 23 - NC_085927.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 191B-like Neighboring gene uncharacterized LOC134730112 Neighboring gene transmembrane protein 191A Neighboring gene serpin family D member 1 Neighboring gene synaptosome associated protein 29 Neighboring gene CRK like proto-oncogene, adaptor protein Neighboring gene small nucleolar RNA U3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol 4-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4-kinase alpha
Names
putative inactive phosphatidylinositol 4-kinase alpha-like protein P1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_085927.1 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    30414241..30565263 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034948745.4 → XP_034804636.2  phosphatidylinositol 4-kinase alpha isoform X4

    UniProtKB/TrEMBL
    A0A2R9B713

  2. XM_034948743.4 → XP_034804634.2  phosphatidylinositol 4-kinase alpha isoform X2

    UniProtKB/TrEMBL
    A0A2R9B713

  3. XM_034948744.3 → XP_034804635.1  phosphatidylinositol 4-kinase alpha isoform X3

    UniProtKB/TrEMBL
    A0A2R9B713
    Conserved Domains (2) summary
    cd00871
    Location:1538 → 1713
    PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
    cd05167
    Location:1774 → 2092
    PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha

  4. XM_034948740.3 → XP_034804631.1  phosphatidylinositol 4-kinase alpha isoform X1

    UniProtKB/TrEMBL
    A0A2R9B713
    Conserved Domains (2) summary
    cd00871
    Location:1560 → 1735
    PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
    cd05167
    Location:1796 → 2114
    PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha

  5. XM_063603229.1 → XP_063459299.1  phosphatidylinositol 4-kinase alpha isoform X6

    UniProtKB/TrEMBL
    A0A2R9B713

  6. XM_034948746.3 → XP_034804637.1  phosphatidylinositol 4-kinase alpha isoform X5

    UniProtKB/TrEMBL
    A0A2R9B713
    Conserved Domains (2) summary
    cd00871
    Location:1506 → 1681
    PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
    cd05167
    Location:1742 → 2060
    PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha
Nucleotide Protein
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