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EDEM2 ER degradation enhancing alpha-mannosidase like protein 2 [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100980744, updated on 8-Mar-2024

Summary

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Gene symbol
EDEM2
Gene description
ER degradation enhancing alpha-mannosidase like protein 2
See related
Ensembl:ENSPPAG00000035737
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See EDEM2 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 21 NC_073270.2 (40847884..40879826, complement)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 20 NC_073269.1 (40840988..40872861, complement)

Chromosome 21 - NC_073270.2Genomic Context describing neighboring genes Neighboring gene transient receptor potential cation channel subfamily C member 4 associated protein Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC134729669 Neighboring gene small nucleolar RNA SNORD56 Neighboring gene protein C receptor Neighboring gene metallothionein-1L

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in endoplasmic reticulum mannose trimming IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mannose trimming involved in glycoprotein ERAD pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ER degradation-enhancing alpha-mannosidase-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073270.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    40847884..40879826 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003831837.5 → XP_003831885.1  ER degradation-enhancing alpha-mannosidase-like protein 2

    UniProtKB/TrEMBL
    A0A2R9B6J8, A0A2R9B6K6
    Related
    ENSPPAP00000025203.1
    Conserved Domains (1) summary
    pfam01532
    Location:42 → 480
    Glyco_hydro_47; Glycosyl hydrolase family 47
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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