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SQLE squalene epoxidase [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100976805, updated on 8-Mar-2024

Summary

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Gene symbol
SQLE
Gene description
squalene epoxidase
See related
Ensembl:ENSPPAG00000044116
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See SQLE in Genome Data Viewer
Location:
chromosome: 7
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 7 NC_073256.2 (142421180..142445046)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 8 NC_073257.1 (117932264..117956167)

Chromosome 7 - NC_073256.2Genomic Context describing neighboring genes Neighboring gene magnesium transporter MRS2 homolog, mitochondrial-like Neighboring gene zinc finger protein 572 Neighboring gene WASH complex subunit 5 Neighboring gene NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables squalene monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cholesterol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
squalene monooxygenase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073256.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    142421180..142445046
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034966577.3 → XP_034822468.1  squalene monooxygenase isoform X3

    Conserved Domains (2) summary
    PRK06185
    Location:38 → 114
    PRK06185; FAD-dependent oxidoreductase
    cl21454
    Location:82 → 353
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  2. XM_008973922.3 → XP_008972170.1  squalene monooxygenase isoform X2

    UniProtKB/TrEMBL
    A0A2R9CP89
    Related
    ENSPPAP00000043163.1
    Conserved Domains (2) summary
    COG0654
    Location:66 → 440
    UbiH; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]
    cl21454
    Location:218 → 489
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  3. XM_003820461.5 → XP_003820509.1  squalene monooxygenase isoform X1

    UniProtKB/TrEMBL
    A0A2R9CMG7, A0A2R9CP89
    Related
    ENSPPAP00000043161.1
    Conserved Domains (2) summary
    COG0654
    Location:124 → 498
    UbiH; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]
    cl21454
    Location:276 → 547
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
Nucleotide Protein
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