U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

HSD17B4 hydroxysteroid 17-beta dehydrogenase 4 [ Otolemur garnettii (small-eared galago) ]

Gene ID: 100966879, updated on 8-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
HSD17B4
Gene description
hydroxysteroid 17-beta dehydrogenase 4
See related
Ensembl:ENSOGAG00000002904
Gene type
protein coding
RefSeq status
MODEL
Organism
Otolemur garnettii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes; Galagidae; Otolemur
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See HSD17B4 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
24
Annotation release Status Assembly Chr Location
102 current OtoGar3 (GCF_000181295.1) Unplaced Scaffold NW_003852425.1 (1661831..1731722, complement)

NW_003852425.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 170 member A Neighboring gene 60S ribosomal protein L15-like Neighboring gene TNF alpha induced protein 8 Neighboring gene 60S ribosomal protein L31 pseudogene

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NW_003852425 Unplaced Scaffold Reference OtoGar3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
peroxisomal multifunctional enzyme type 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Otolemur garnettii Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference OtoGar3

Genomic

  1. NW_003852425.1 Reference OtoGar3

    Range
    1661831..1731722 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003788894.3 → XP_003788942.1  peroxisomal multifunctional enzyme type 2 isoform X1

    UniProtKB/TrEMBL
    H0WLQ0
    Conserved Domains (5) summary
    PLN02864
    Location:190 → 467
    PLN02864; enoyl-CoA hydratase
    cd03448
    Location:347 → 467
    HDE_HSD; HDE_HSD The R-hydratase-like hot dog fold of the 17-beta-hydroxysteriod dehydrogenase (HSD), and Hydratase-Dehydrogenase-Epimerase (HDE) proteins. Other enzymes with this fold include MaoC dehydratase, and the fatty acid synthase beta subunit.
    pfam02036
    Location:490 → 593
    SCP2; SCP-2 sterol transfer family
    cl00509
    Location:189 → 305
    hot_dog; The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated ...
    cl21454
    Location:1 → 117
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  2. XM_012804624.2 → XP_012660078.1  peroxisomal multifunctional enzyme type 2 isoform X2

    UniProtKB/TrEMBL
    H0WLQ0
    Related
    ENSOGAP00000002602.2, ENSOGAT00000002908.2
    Conserved Domains (5) summary
    PLN02864
    Location:290 → 567
    PLN02864; enoyl-CoA hydratase
    cd05353
    Location:2 → 217
    hydroxyacyl-CoA-like_DH_SDR_c-like; (3R)-hydroxyacyl-CoA dehydrogenase-like, classical(c)-like SDRs
    cd03448
    Location:447 → 567
    HDE_HSD; HDE_HSD The R-hydratase-like hot dog fold of the 17-beta-hydroxysteriod dehydrogenase (HSD), and Hydratase-Dehydrogenase-Epimerase (HDE) proteins. Other enzymes with this fold include MaoC dehydratase, and the fatty acid synthase beta subunit.
    pfam02036
    Location:590 → 693
    SCP2; SCP-2 sterol transfer family
    cl00509
    Location:289 → 405
    hot_dog; The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.