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PIK3C2A phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha [ Otolemur garnettii (small-eared galago) ]

Gene ID: 100965435, updated on 8-Mar-2024

Summary

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Gene symbol
PIK3C2A
Gene description
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
Gene type
protein coding
RefSeq status
MODEL
Organism
Otolemur garnettii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes; Galagidae; Otolemur
Orthologs
human mouse all
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Genomic context

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See PIK3C2A in Genome Data Viewer
Location:
chromosome: Un
Exon count:
33
Annotation release Status Assembly Chr Location
102 current OtoGar3 (GCF_000181295.1) Unplaced Scaffold NW_003852396.1 (45871037..45980647, complement)

NW_003852396.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD14 Neighboring gene small nucleolar RNA SNORD14 Neighboring gene ribosomal protein S13 Neighboring gene 40S ribosomal protein S24 pseudogene Neighboring gene zinc finger protein 215 pseudogene Neighboring gene nucleobindin 2 Neighboring gene 60S ribosomal protein L30

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_003852396 Unplaced Scaffold Reference OtoGar3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Otolemur garnettii Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference OtoGar3

Genomic

  1. NW_003852396.1 Reference OtoGar3

    Range
    45871037..45980647 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003781141.3 → XP_003781189.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

    Conserved Domains (6) summary
    cd07289
    Location:1428 → 1536
    PX_PI3K_C2_alpha; The phosphoinositide binding Phox Homology Domain of the Alpha Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:679 → 851
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1562 → 1683
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:872 → 1040
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    cd05176
    Location:1045 → 1397
    PI3Kc_C2_alpha; Catalytic domain of Class II Phosphoinositide 3-kinase alpha
    pfam00794
    Location:411 → 514
    PI3K_rbd; PI3-kinase family, ras-binding domain
Nucleotide Protein
Heading Accession and Version

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