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PTEN phosphatase and tensin homolog [ Otolemur garnettii (small-eared galago) ]

Gene ID: 100959283, updated on 8-Mar-2024

Summary

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Gene symbol
PTEN
Gene description
phosphatase and tensin homolog
See related
Ensembl:ENSOGAG00000031772
Gene type
protein coding
RefSeq status
MODEL
Organism
Otolemur garnettii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes; Galagidae; Otolemur
Orthologs
human mouse all
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Genomic context

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See PTEN in Genome Data Viewer
Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
102 current OtoGar3 (GCF_000181295.1) Unplaced Scaffold NW_003852403.1 (33374202..33473140)

NW_003852403.1Genomic Context describing neighboring genes Neighboring gene 3'-phosphoadenosine 5'-phosphosulfate synthase 2 Neighboring gene ATPase family AAA domain containing 1 Neighboring gene U6 spliceosomal RNA Neighboring gene 60S ribosomal protein L37 pseudogene Neighboring gene putative 60S ribosomal protein L39-like 5 Neighboring gene renalase, FAD dependent amine oxidase

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_003852403 Unplaced Scaffold Reference OtoGar3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell motility IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Otolemur garnettii Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference OtoGar3

Genomic

  1. NW_003852403.1 Reference OtoGar3

    Range
    33374202..33473140
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003783677.3 → XP_003783725.1  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

    See identical proteins and their annotated locations for XP_003783725.1

    Related
    ENSOGAP00000018538.1, ENSOGAT00000024405.1
    Conserved Domains (2) summary
    smart00404
    Location:92 → 183
    PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
    pfam10409
    Location:188 → 349
    PTEN_C2; C2 domain of PTEN tumour-suppressor protein
Nucleotide Protein
Heading Accession and Version

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