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TJP2 tight junction protein 2 [ Otolemur garnettii (small-eared galago) ]

Gene ID: 100958865, updated on 8-Mar-2024

Summary

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Gene symbol
TJP2
Gene description
tight junction protein 2
See related
Ensembl:ENSOGAG00000014757
Gene type
protein coding
RefSeq status
MODEL
Organism
Otolemur garnettii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes; Galagidae; Otolemur
Orthologs
human mouse all
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Genomic context

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See TJP2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
24
Annotation release Status Assembly Chr Location
102 current OtoGar3 (GCF_000181295.1) Unplaced Scaffold NW_003852401.1 (27234238..27319770)

NW_003852401.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene U6 snRNA-associated Sm-like protein LSm3 pseudogene Neighboring gene U6 spliceosomal RNA Neighboring gene endosomal transmembrane epsin interactor 1 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_003852401 Unplaced Scaffold Reference OtoGar3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Otolemur garnettii Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference OtoGar3

Genomic

  1. NW_003852401.1 Reference OtoGar3

    Range
    27234238..27319770
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003782929.3 → XP_003782977.1  tight junction protein ZO-2 isoform X1

    UniProtKB/TrEMBL
    H0XBW6
    Conserved Domains (5) summary
    cd12027
    Location:611 → 673
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:707 → 886
    GuKc; Guanylate kinase homologues
    smart00228
    Location:315 → 392
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12871
    Location:157 → 254
    PRP38_assoc; Pre-mRNA-splicing factor 38-associated hydrophilic C-term

  2. XM_023508231.1 → XP_023363999.1  tight junction protein ZO-2 isoform X2

    UniProtKB/TrEMBL
    H0XBW6
    Conserved Domains (5) summary
    cd12027
    Location:611 → 673
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:707 → 886
    GuKc; Guanylate kinase homologues
    smart00228
    Location:315 → 392
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl25887
    Location:167 → 350
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

  3. XM_003782930.3 → XP_003782978.1  tight junction protein ZO-2 isoform X3

    UniProtKB/TrEMBL
    H0XBW6
    Related
    ENSOGAP00000013230.2, ENSOGAT00000014770.2
    Conserved Domains (5) summary
    cd12027
    Location:615 → 677
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:711 → 890
    GuKc; Guanylate kinase homologues
    smart00228
    Location:319 → 396
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12871
    Location:161 → 258
    PRP38_assoc; Pre-mRNA-splicing factor 38-associated hydrophilic C-term
Nucleotide Protein
Heading Accession and Version

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