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MASP2 MBL associated serine protease 2 [ Otolemur garnettii (small-eared galago) ]

Gene ID: 100957137, updated on 8-Mar-2024

Summary

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Gene symbol
MASP2
Gene description
MBL associated serine protease 2
See related
Ensembl:ENSOGAG00000031666
Gene type
protein coding
RefSeq status
MODEL
Organism
Otolemur garnettii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes; Galagidae; Otolemur
Orthologs
human mouse all
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Genomic context

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See MASP2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
102 current OtoGar3 (GCF_000181295.1) Unplaced Scaffold NW_003852462.1 (7765007..7779520, complement)

NW_003852462.1Genomic Context describing neighboring genes Neighboring gene chromosome unknown C1orf127 homolog Neighboring gene TAR DNA binding protein Neighboring gene spermidine synthase Neighboring gene exosome component 10

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_003852462 Unplaced Scaffold Reference OtoGar3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation, lectin pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mannan-binding lectin serine protease 2
Names
mannan binding lectin serine peptidase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Otolemur garnettii Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference OtoGar3

Genomic

  1. NW_003852462.1 Reference OtoGar3

    Range
    7765007..7779520 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003793266.3 → XP_003793314.1  mannan-binding lectin serine protease 2 isoform X1

    UniProtKB/TrEMBL
    H0XJI8
    Related
    ENSOGAP00000016278.1, ENSOGAT00000032562.1
    Conserved Domains (7) summary
    smart00020
    Location:447 → 682
    Tryp_SPc; Trypsin-like serine protease
    smart00032
    Location:303 → 364
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
    smart00179
    Location:141 → 179
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:27 → 139
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:448 → 685
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:369 → 433
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:187 → 296
    CUB; CUB domain

  2. XM_012807304.2 → XP_012662758.1  mannan-binding lectin serine protease 2 isoform X2

    Conserved Domains (2) summary
    smart00179
    Location:141 → 179
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:27 → 139
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Nucleotide Protein
Heading Accession and Version

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