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SEMA7A semaphorin 7A (JohnMiltonHagen blood group) [ Otolemur garnettii (small-eared galago) ]

Gene ID: 100952899, updated on 8-Mar-2024

Summary

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Gene symbol
SEMA7A
Gene description
semaphorin 7A (JohnMiltonHagen blood group)
See related
Ensembl:ENSOGAG00000001257
Gene type
protein coding
RefSeq status
MODEL
Organism
Otolemur garnettii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes; Galagidae; Otolemur
Orthologs
human mouse all
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Genomic context

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See SEMA7A in Genome Data Viewer
Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
102 current OtoGar3 (GCF_000181295.1) Unplaced Scaffold NW_003852406.1 (26364586..26388939, complement)

NW_003852406.1Genomic Context describing neighboring genes Neighboring gene cholesterol side-chain cleavage enzyme, mitochondrial Neighboring gene 60S ribosomal protein L13a pseudogene Neighboring gene ubiquitin like 7 Neighboring gene vesicular, overexpressed in cancer, prosurvival protein 1 pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_003852406 Unplaced Scaffold Reference OtoGar3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chemorepellent activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables semaphorin receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of axon extension involved in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neural crest cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of axon extension IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of macrophage cytokine production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in semaphorin-plexin signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
semaphorin-7A
Names
semaphorin 7A (John Milton Hagen blood group)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Otolemur garnettii Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference OtoGar3

Genomic

  1. NW_003852406.1 Reference OtoGar3

    Range
    26364586..26388939 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003784509.3 → XP_003784557.1  semaphorin-7A isoform X2

    Conserved Domains (2) summary
    cd11243
    Location:71 → 475
    Sema_7A; The Sema domain, a protein interacting module, of semaphorin 7A (Sema7A, also called CD108)
    pfam01437
    Location:477 → 504
    PSI; Plexin repeat

  2. XM_003784507.3 → XP_003784555.1  semaphorin-7A isoform X1

    UniProtKB/TrEMBL
    H0WI85
    Related
    ENSOGAP00000001127.2, ENSOGAT00000001259.2
    Conserved Domains (2) summary
    cd11243
    Location:71 → 489
    Sema_7A; The Sema domain, a protein interacting module, of semaphorin 7A (Sema7A, also called CD108)
    pfam01437
    Location:491 → 518
    PSI; Plexin repeat

  3. XM_003784508.3 → XP_003784556.1  semaphorin-7A isoform X3

    Conserved Domains (2) summary
    cd11243
    Location:27 → 445
    Sema_7A; The Sema domain, a protein interacting module, of semaphorin 7A (Sema7A, also called CD108)
    pfam01437
    Location:447 → 474
    PSI; Plexin repeat
Nucleotide Protein
Heading Accession and Version

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