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HSD17B4 hydroxysteroid 17-beta dehydrogenase 4 [ Sarcophilus harrisii (Tasmanian devil) ]

Gene ID: 100932771, updated on 8-Mar-2024

Summary

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Gene symbol
HSD17B4
Gene description
hydroxysteroid 17-beta dehydrogenase 4
See related
Ensembl:ENSSHAG00000005224
Gene type
protein coding
RefSeq status
MODEL
Organism
Sarcophilus harrisii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus
Orthologs
human mouse all
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Genomic context

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See HSD17B4 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
24
Annotation release Status Assembly Chr Location
103 current mSarHar1.11 (GCF_902635505.1) 1 NC_045426.1 (239150239..239289200)
102 previous assembly Devil_ref v7.0 (GCF_000189315.1) 2 Unlocalized Scaffold NW_003824197.1 (145802..284300, complement)

Chromosome 1 - NC_045426.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105749467 Neighboring gene Dmx like 1 Neighboring gene TNF alpha induced protein 8 Neighboring gene uncharacterized LOC116419355 Neighboring gene splicing factor 3A subunit 3 pseudogene Neighboring gene proline rich 16

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
peroxisomal multifunctional enzyme type 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sarcophilus harrisii Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mSarHar1.11 Primary Assembly

Genomic

  1. NC_045426.1 Reference mSarHar1.11 Primary Assembly

    Range
    239150239..239289200
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003762919.4 → XP_003762967.1  peroxisomal multifunctional enzyme type 2

    UniProtKB/TrEMBL
    G3VS44
    Related
    ENSSHAP00000005999.1, ENSSHAT00000006053.2
    Conserved Domains (6) summary
    PLN02864
    Location:316 → 605
    PLN02864; enoyl-CoA hydratase
    cd05353
    Location:5 → 254
    hydroxyacyl-CoA-like_DH_SDR_c-like; (3R)-hydroxyacyl-CoA dehydrogenase-like, classical(c)-like SDRs
    PRK05653
    Location:6 → 226
    fabG; 3-ketoacyl-(acyl-carrier-protein) reductase; Validated
    cd03448
    Location:485 → 605
    HDE_HSD; HDE_HSD The R-hydratase-like hot dog fold of the 17-beta-hydroxysteriod dehydrogenase (HSD), and Hydratase-Dehydrogenase-Epimerase (HDE) proteins. Other enzymes with this fold include MaoC dehydratase, and the fatty acid synthase beta subunit.
    pfam02036
    Location:628 → 731
    SCP2; SCP-2 sterol transfer family
    cl00509
    Location:326 → 439
    hot_dog; The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated ...
Nucleotide Protein
Heading Accession and Version

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