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PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 [ Sarcophilus harrisii (Tasmanian devil) ]

Gene ID: 100922064, updated on 8-Mar-2024

Summary

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Gene symbol
PFKFB3
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
See related
Ensembl:ENSSHAG00000013183
Gene type
protein coding
RefSeq status
MODEL
Organism
Sarcophilus harrisii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus
Orthologs
human mouse all
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Genomic context

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See PFKFB3 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
17
Annotation release Status Assembly Chr Location
103 current mSarHar1.11 (GCF_902635505.1) 5 NC_045430.1 (122361585..122448546)
102 previous assembly Devil_ref v7.0 (GCF_000189315.1) 5 Unlocalized Scaffold NW_003843633.1 (1123495..1205640)

Chromosome 5 - NC_045430.1Genomic Context describing neighboring genes Neighboring gene basic helix-loop-helix ARNT like 2 Neighboring gene RNA binding motif protein 17 Neighboring gene U6 spliceosomal RNA Neighboring gene protein kinase C theta

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sarcophilus harrisii Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mSarHar1.11 Primary Assembly

Genomic

  1. NC_045430.1 Reference mSarHar1.11 Primary Assembly

    Range
    122361585..122448546
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012550866.3 → XP_012406320.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X3

    Conserved Domains (3) summary
    pfam00300
    Location:229 → 412
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:4 → 226
    6PF2K; 6-phosphofructo-2-kinase
    pfam13671
    Location:17 → 171
    AAA_33; AAA domain

  2. XM_012550865.3 → XP_012406319.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X2

    UniProtKB/TrEMBL
    G3WJ62
    Related
    ENSSHAP00000015467.2, ENSSHAT00000015594.2
    Conserved Domains (3) summary
    pfam00300
    Location:249 → 432
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:26 → 246
    6PF2K; 6-phosphofructo-2-kinase
    pfam13671
    Location:37 → 191
    AAA_33; AAA domain

  3. XM_003771410.4 → XP_003771458.2  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X1

    UniProtKB/TrEMBL
    G3WJ62
    Conserved Domains (3) summary
    pfam00300
    Location:249 → 432
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:26 → 246
    6PF2K; 6-phosphofructo-2-kinase
    pfam13671
    Location:37 → 191
    AAA_33; AAA domain
Nucleotide Protein
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