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SFRP1 secreted frizzled related protein 1 [ Sarcophilus harrisii (Tasmanian devil) ]

Gene ID: 100920776, updated on 8-Mar-2024

Summary

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Gene symbol
SFRP1
Gene description
secreted frizzled related protein 1
See related
Ensembl:ENSSHAG00000015287
Gene type
protein coding
RefSeq status
MODEL
Organism
Sarcophilus harrisii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus
Orthologs
human mouse all
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Genomic context

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See SFRP1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
3
Annotation release Status Assembly Chr Location
103 current mSarHar1.11 (GCF_902635505.1) 2 NC_045427.1 (128005483..128078854, complement)
102 previous assembly Devil_ref v7.0 (GCF_000189315.1) 1 Unlocalized Scaffold NW_003816720.1 (1810810..1818871, complement)

Chromosome 2 - NC_045427.1Genomic Context describing neighboring genes Neighboring gene transcriptional and immune response regulator Neighboring gene zinc finger matrin-type 4 Neighboring gene uncharacterized LOC116421099 Neighboring gene golgin A7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in non-canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
secreted frizzled-related protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sarcophilus harrisii Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mSarHar1.11 Primary Assembly

Genomic

  1. NC_045427.1 Reference mSarHar1.11 Primary Assembly

    Range
    128005483..128078854 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023494733.2 → XP_023350501.2  secreted frizzled-related protein 1

    UniProtKB/TrEMBL
    G3WRF0
    Related
    ENSSHAP00000018005.1, ENSSHAT00000018154.2
    Conserved Domains (2) summary
    cd07443
    Location:52 → 175
    CRD_SFRP1; Cysteine-rich domain of the secreted frizzled-related protein 1 (SFRP1), a regulator of Wnt activity
    cd03580
    Location:183 → 306
    NTR_Sfrp1_like; NTR domain, Secreted frizzled-related protein (Sfrp) 1-like subfamily; composed of proteins similar to human Sfrp1, Sfrp2 and Sfrp5. Sfrps are soluble proteins containing an NTR domain C-terminal to a cysteine-rich Frizzled domain. They show diverse ...
Nucleotide Protein
Heading Accession and Version

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