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DYSF dysferlin [ Sarcophilus harrisii (Tasmanian devil) ]

Gene ID: 100917476, updated on 8-Mar-2024

Summary

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Gene symbol
DYSF
Gene description
dysferlin
See related
Ensembl:ENSSHAG00000000572
Gene type
protein coding
RefSeq status
MODEL
Organism
Sarcophilus harrisii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus
Orthologs
human mouse all
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Genomic context

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See DYSF in Genome Data Viewer
Location:
chromosome: 2
Exon count:
57
Annotation release Status Assembly Chr Location
103 current mSarHar1.11 (GCF_902635505.1) 2 NC_045427.1 (20831574..21042618, complement)
102 previous assembly Devil_ref v7.0 (GCF_000189315.1) 1 Unlocalized Scaffold NW_003817456.1 (2167..147516, complement)

Chromosome 2 - NC_045427.1Genomic Context describing neighboring genes Neighboring gene exocyst complex component 6B Neighboring gene cytochrome P450 26B1 Neighboring gene zinc finger protein 638 Neighboring gene poly(A) binding protein interacting protein 2B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent phospholipid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in T-tubule organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in macrophage activation involved in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monocyte activation involved in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of phagocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in plasma membrane repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in vesicle fusion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in T-tubule IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: dysferlin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sarcophilus harrisii Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mSarHar1.11 Primary Assembly

Genomic

  1. NC_045427.1 Reference mSarHar1.11 Primary Assembly

    Range
    20831574..21042618 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031949204.1 → XP_031805064.1  LOW QUALITY PROTEIN: dysferlin

    Related
    ENSSHAT00000000652.2
    Conserved Domains (11) summary
    cd04011
    Location:209 → 318
    C2B_Ferlin; C2 domain second repeat in Ferlin
    cd04017
    Location:1187 → 1315
    C2D_Ferlin; C2 domain fourth repeat in Ferlin
    cd04018
    Location:372 → 546
    C2C_Ferlin; C2 domain third repeat in Ferlin
    cd04037
    Location:1751 → 1874
    C2E_Ferlin; C2 domain fifth repeat in Ferlin
    cd08373
    Location:21 → 123
    C2A_Ferlin; C2 domain first repeat in Ferlin
    cd08374
    Location:1985 → 2116
    C2F_Ferlin; C2 domain sixth repeat in Ferlin
    smart00693
    Location:981 → 1037
    DysFN; Dysferlin domain, N-terminal region
    pfam08150
    Location:821 → 894
    FerB; FerB (NUC096) domain
    pfam08151
    Location:316 → 366
    FerI; FerI (NUC094) domain
    pfam08165
    Location:733 → 787
    FerA; FerA (NUC095) domain
    pfam16165
    Location:2129 → 2216
    Ferlin_C; Ferlin C-terminus
Nucleotide Protein
Heading Accession and Version

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