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LOC100911252 peptidyl-prolyl cis-trans isomerase A-like [ Rattus norvegicus (Norway rat) ]

Gene ID: 100911252, updated on 28-Oct-2024

Summary

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Symbol
LOC100911252provided by RGD
Full Name
peptidyl-prolyl cis-trans isomerase A-likeprovided by RGD
Primary source
RGD:6493676
See related
AllianceGenome:RGD:6493676
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in apoptotic process; protein folding; and protein peptidyl-prolyl isomerization. Predicted to be located in cytoplasm; extracellular region; and nucleus. Human ortholog(s) of this gene implicated in cholangiocarcinoma and human immunodeficiency virus infectious disease. Orthologous to several human genes including PPIA (peptidylprolyl isomerase A). [provided by Alliance of Genome Resources, Oct 2024]
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Genomic context

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See LOC100911252 in Genome Data Viewer
Location:
4q21
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (42794961..42795713)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (41828873..41829619)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (40004617..40005358)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene taste receptor type 2 member 7-like Neighboring gene uncharacterized LOC102548489 Neighboring gene transmembrane protein 168 Neighboring gene small nucleolar RNA SNORA44

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Peptidyl-prolyl cis-trans isomerase A participates in the selenium transport into the rat brain. Yoshida S, et al. J Biol Inorg Chem, 2021 Dec. PMID 34550449
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Peptidyl-prolyl cis-trans isomerase A participates in the selenium transport into the rat brain.
    Title: Peptidyl-prolyl cis-trans isomerase A participates in the selenium transport into the rat brain.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables peptidyl-prolyl cis-trans isomerase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
  
involved_in protein folding IEA
Inferred from Electronic Annotation
more info
  
involved_in protein peptidyl-prolyl isomerization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
peptidyl-prolyl cis-trans isomerase A-like
Names
TRIMCyp-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    42794961..42795713
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039108606.2 → XP_038964534.1  peptidyl-prolyl cis-trans isomerase A-like

    UniProtKB/TrEMBL
    A0A8I6A629, A6IKT9
    Conserved Domains (1) summary
    cd01926
    Location:4 → 162
    cyclophilin_ABH_like; Cyclophilin A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which accelerates protein folding ...
Nucleotide Protein Strain
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