SOX2 SRY-box transcription factor 2 [Capra hircus (goat)] - Gene

Summary

Gene symbol: SOX2
Gene description: SRY-box transcription factor 2
See related: EnsemblRapid:ENSCHIG00000011126
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Capra hircus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Capra
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
102	current	ASM170441v1 (GCF_001704415.1)	1	NC_030808.1 (85009956..85010918, complement)
101	previous assembly	CHIR_1.0 (GCF_000317765.1)	1	NC_022293.1 (83700481..83701292, complement)

Chromosome 1 - NC_030808.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

Sox2 (e-PCR), detects polymorphism
- UniSTS:474706

Sox2 (e-PCR), detects polymorphism
- UniSTS:548082

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in anatomical structure morphogenesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: transcription factor SOX-2

Names: SRY (sex determining region Y)-box 2; SRY-box 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001285672.1 → NP_001272601.1 transcription factor SOX-2

See identical proteins and their annotated locations for NP_001272601.1

Status: PROVISIONAL

Source sequence(s)

JQ290347

UniProtKB/TrEMBL

H6WS81

Related

ENSCHIP00000007702.1, ENSCHIT00000015450.1

Conserved Domains (2) summary

cd01388
Location:43 → 114

SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...

pfam12336
Location:113 → 203

SOXp; SOX transcription factor