HK2 hexokinase 2 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: HK2provided by VGNC
Official Full Name: hexokinase 2provided by VGNC
Primary source: VGNC:VGNC:41699
See related: Ensembl:ENSCAFG00845016792
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	17	NC_051821.1 (49149327..49211264, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	17	NC_006599.4 (47929800..47991763, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	17	NC_049238.1 (48791741..48853532, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	17	NC_049277.1 (48164479..48226250, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	17	NC_049758.1 (48228923..48290663, complement)

Chromosome 17 - NC_051821.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables D-glucose binding	IEA Inferred from Electronic Annotation more info	PubMed
enables fructokinase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables glucokinase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables mannokinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in glucose 6-phosphate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in glycolytic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in intracellular glucose homeostasis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: LOW QUALITY PROTEIN: hexokinase-2; hexokinase-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051821.1 Reference ROS_Cfam_1.0

Range

49149327..49211264 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038691612.1 → XP_038547540.1 hexokinase-2

UniProtKB/TrEMBL

A0A8C0NUW4, A0A8C0R115, A0A8C0RZJ3, A0A8I3P147

Related

ENSCAFP00845023451.1, ENSCAFT00845029857.1

Conserved Domains (3) summary

PTZ00107
Location:12 → 460

PTZ00107; hexokinase; Provisional

pfam00349
Location:471 → 667

Hexokinase_1

pfam03727
Location:673 → 907

Hexokinase_2

Alternate UMICH_Zoey_3.1

Genomic

NC_049277.1 Alternate UMICH_Zoey_3.1

Range

48164479..48226250 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038499056.1 → XP_038354984.1 hexokinase-2

Conserved Domains (3) summary

PTZ00107
Location:12 → 460

PTZ00107; hexokinase; Provisional

pfam00349
Location:471 → 667

Hexokinase_1

pfam03727
Location:673 → 907

Hexokinase_2

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049758.1 Alternate UNSW_CanFamBas_1.0

Range

48228923..48290663 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038625685.1 → XP_038481613.1 hexokinase-2

Conserved Domains (3) summary

PTZ00107
Location:12 → 460

PTZ00107; hexokinase; Provisional

pfam00349
Location:471 → 667

Hexokinase_1

pfam03727
Location:673 → 907

Hexokinase_2

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049238.1 Alternate UU_Cfam_GSD_1.0

Range

48791741..48853532 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038561644.1 → XP_038417572.1 LOW QUALITY PROTEIN: hexokinase-2

UniProtKB/TrEMBL

A0A8C0NUW4, A0A8C0R115, A0A8C0RZJ3, A0A8I3P147

Conserved Domains (3) summary

PTZ00107
Location:12 → 460

PTZ00107; hexokinase; Provisional

pfam00349
Location:471 → 667

Hexokinase_1

pfam03727
Location:673 → 907

Hexokinase_2

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

47929800..47991763 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038453237.1 → XP_038309165.1 hexokinase-2

UniProtKB/TrEMBL

A0A8C0NUW4, A0A8C0R115, A0A8C0RZJ3, A0A8I3P147

Conserved Domains (3) summary

PTZ00107
Location:12 → 460

PTZ00107; hexokinase; Provisional

pfam00349
Location:471 → 667

Hexokinase_1

pfam03727
Location:673 → 907

Hexokinase_2