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MIR5191 microRNA 5191 [ Homo sapiens (human) ]

Gene ID: 100847050, updated on 17-Sep-2024

Summary

Official Symbol
MIR5191provided by HGNC
Official Full Name
microRNA 5191provided by HGNC
Primary source
HGNC:HGNC:43497
See related
Ensembl:ENSG00000264802 miRBase:MI0018170; AllianceGenome:HGNC:43497
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

See MIR5191 in Genome Data Viewer
Location:
1q32.1
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (201719508..201719627)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (200977292..200977411)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (201688636..201688755)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124904484 Neighboring gene CSRP1 antisense RNA 1 Neighboring gene ribosomal protein S10 pseudogene 7 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:201534809-201535310 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:201535311-201535810 Neighboring gene CRISPRi-validated cis-regulatory element chr1.10615 Neighboring gene neuron navigator 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:201560646-201561209 Neighboring gene uncharacterized LOC124904482 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:201591323-201591707 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:201597565-201598066 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:201653379-201653880 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:201653881-201654380 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:201659372-201659872 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:201672490-201673062 Neighboring gene IPO9 antisense RNA 1 Neighboring gene Sharpr-MPRA regulatory region 1273 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:201688752-201689398 Neighboring gene uncharacterized LOC124904483 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:201693607-201694108 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:201706423-201706974 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:201706975-201707524 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1694 Neighboring gene RNA, U6 small nuclear 501, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:201721153-201721652 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr1:201757192-201757692 Neighboring gene microRNA 1231

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_049823.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AL645504
    Related
    ENST00000577455.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    201719508..201719627
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    200977292..200977411
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)