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MIR5092 microRNA 5092 [ Homo sapiens (human) ]

Gene ID: 100847039, updated on 10-Oct-2023

Summary

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Official Symbol
MIR5092provided by HGNC
Official Full Name
microRNA 5092provided by HGNC
Primary source
HGNC:HGNC:43467
See related
Ensembl:ENSG00000264986 miRBase:MI0017981; AllianceGenome:HGNC:43467
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

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Location:
3q21.2
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (125151465..125151552, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (127879828..127879915, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (124870309..124870396, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124906278 Neighboring gene solute carrier family 12 member 8 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:124826256-124826756 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:124826757-124827257 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20412 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20413 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20414 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20415 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20416 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:124839347-124839853 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:124839854-124840359 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20417 Neighboring gene RNA, U6 small nuclear 230, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20418 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14661 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:124860668-124861491 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:124862005-124862958 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20421 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20422 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20423 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20424 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20425 Neighboring gene NANOG hESC enhancer GRCh37_chr3:124872987-124873488 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14662 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20426 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20427 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:124930713-124931312 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14664 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14665 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr3:124950809-124952008 Neighboring gene zinc finger protein 148 Neighboring gene deoxyuridine triphosphatase pseudogene 1 Neighboring gene NANOG hESC enhancer GRCh37_chr3:125058886-125059484 Neighboring gene DNAJB6 pseudogene 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Detection of novel human MiRNAs responding to X-ray irradiation. Ding N, et al. J Radiat Res, 2011. PMID 21785231
  2. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Other Names

  • hsa-mir-5092

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_049815.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC055752
    Related
    ENST00000583139.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    125151465..125151552 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    127879828..127879915 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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