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DEGS2 delta 4-desaturase, sphingolipid 2 [ Sus scrofa (pig) ]

Gene ID: 100739329, updated on 17-Aug-2024

Summary

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Official Symbol
DEGS2provided by VGNC
Official Full Name
delta 4-desaturase, sphingolipid 2provided by VGNC
Primary source
VGNC:VGNC:87242
See related
Ensembl:ENSSSCG00000002512
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Biased expression in ovary (RPKM 1.7), lung (RPKM 1.3) and 4 other tissues See more
Orthologs
human mouse all
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Genomic context

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See DEGS2 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
9
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 7 NC_010449.5 (121058102..121131612, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 7 NC_010449.4 (128592520..128599969)

Chromosome 7 - NC_010449.5Genomic Context describing neighboring genes Neighboring gene EMAP like 1 Neighboring gene Enah/Vasp-like Neighboring gene microRNA mir-342 Neighboring gene YY1 transcription factor Neighboring gene solute carrier family 25 member 29

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables sphingolipid delta-4 desaturase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sphingosine hydroxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphinganine metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sphingolipid delta(4)-desaturase/C4-monooxygenase DES2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010449.5 Reference Sscrofa11.1 Primary Assembly

    Range
    121058102..121131612 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021099703.1 → XP_020955362.1  sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 isoform X3

    UniProtKB/TrEMBL
    A0A4X1TK19
    Conserved Domains (1) summary
    cd03508
    Location:1 → 278
    Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...

  2. XM_021099700.1 → XP_020955359.1  sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 isoform X1

    UniProtKB/TrEMBL
    A0A4X1TK19
    Conserved Domains (1) summary
    cd03508
    Location:70 → 357
    Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...

  3. XM_021099705.1 → XP_020955364.1  sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 isoform X3

    UniProtKB/TrEMBL
    A0A4X1TK19
    Conserved Domains (1) summary
    cd03508
    Location:1 → 278
    Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...

  4. XM_021099701.1 → XP_020955360.1  sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 isoform X2

    UniProtKB/TrEMBL
    A0A4X1TK14, A0A4X1TK19, F1SAQ0
    Related
    ENSSSCP00000002719.3, ENSSSCT00000002790.5
    Conserved Domains (2) summary
    cd03508
    Location:26 → 314
    Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...
    pfam08557
    Location:6 → 42
    Lipid_DES; Sphingolipid Delta4-desaturase (DES)

  5. XM_021099702.1 → XP_020955361.1  sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 isoform X3

    UniProtKB/TrEMBL
    A0A4X1TK19
    Conserved Domains (1) summary
    cd03508
    Location:1 → 278
    Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...

  6. XM_021099704.1 → XP_020955363.1  sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 isoform X3

    UniProtKB/TrEMBL
    A0A4X1TK19
    Conserved Domains (1) summary
    cd03508
    Location:1 → 278
    Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...
Nucleotide Protein
Heading Accession and Version

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