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Mapkapk5 MAPK activated protein kinase 5 [ Cavia porcellus (domestic guinea pig) ]

Gene ID: 100730794, updated on 10-Oct-2024

Summary

Gene symbol
Mapkapk5
Gene description
MAPK activated protein kinase 5
See related
Ensembl:ENSCPOG00000009418
Gene type
protein coding
RefSeq status
MODEL
Organism
Cavia porcellus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Orthologs
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Genomic context

See Mapkapk5 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947499.1 (9694790..9720462)
103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176304.1 (3086092..3113123)

NW_026947499.1Genomic Context describing neighboring genes Neighboring gene acyl-CoA dehydrogenase family member 10 Neighboring gene aldehyde dehydrogenase 2 family member Neighboring gene transmembrane protein 116 Neighboring gene disintegrin and metalloproteinase domain-containing protein 1a-like Neighboring gene PH-30 alpha

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables calcium-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables calcium/calmodulin-dependent protein kinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables mitogen-activated protein kinase binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in negative regulation of TOR signaling IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein autophosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
MAP kinase-activated protein kinase 5
Names
mitogen-activated protein kinase-activated protein kinase 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

  1. NW_026947499.1 Reference mCavPor4.1

    Range
    9694790..9720462
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003462944.5XP_003462992.1  MAP kinase-activated protein kinase 5 isoform X5

    UniProtKB/TrEMBL
    H0VEK7
    Related
    ENSCPOP00000008458.3
    Conserved Domains (2) summary
    smart00220
    Location:26304
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14171
    Location:15304
    STKc_MAPKAPK5; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase-activated protein kinase 5
  2. XM_005000480.4XP_005000537.1  MAP kinase-activated protein kinase 5 isoform X6

    UniProtKB/TrEMBL
    A0A286Y4A1, H0VEK7
    Related
    ENSCPOP00000032661.1
    Conserved Domains (2) summary
    smart00220
    Location:26304
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14171
    Location:15304
    STKc_MAPKAPK5; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase-activated protein kinase 5
  3. XM_063225655.1XP_063081725.1  MAP kinase-activated protein kinase 5 isoform X7

  4. XM_063225651.1XP_063081721.1  MAP kinase-activated protein kinase 5 isoform X1

  5. XM_013144823.3XP_013000277.1  MAP kinase-activated protein kinase 5 isoform X2

    UniProtKB/TrEMBL
    H0VEK7
    Related
    ENSCPOP00000021662.1
    Conserved Domains (2) summary
    smart00220
    Location:26235
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:15235
    PKc_like; Protein Kinases, catalytic domain
  6. XM_063225653.1XP_063081723.1  MAP kinase-activated protein kinase 5 isoform X3

  7. XM_063225654.1XP_063081724.1  MAP kinase-activated protein kinase 5 isoform X4