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Rela RELA proto-oncogene, NF-kB subunit [ Cavia porcellus (domestic guinea pig) ]

Gene ID: 100724366, updated on 8-Mar-2024

Summary

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Gene symbol
Rela
Gene description
RELA proto-oncogene, NF-kB subunit
See related
Ensembl:ENSCPOG00000020593
Gene type
protein coding
RefSeq status
MODEL
Organism
Cavia porcellus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Orthologs
human mouse all
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Genomic context

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See Rela in Genome Data Viewer
Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947500.1 (24416510..24425754, complement)
103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176377.1 (6353301..6361674, complement)

NW_026947500.1Genomic Context describing neighboring genes Neighboring gene pecanex 3 Neighboring gene uncharacterized LOC134470885 Neighboring gene signal-induced proliferation-associated 1 Neighboring gene lysine acetyltransferase 5 Neighboring gene ribonuclease H2 subunit C

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to lipopolysaccharide IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in non-canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to cytokine IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription factor p65
Names
v-rel reticuloendotheliosis viral oncogene homolog A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

  1. NW_026947500.1 Reference mCavPor4.1

    Range
    24416510..24425754 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063227533.1 → XP_063083603.1  transcription factor p65 isoform X3

  2. XM_003468074.5 → XP_003468122.1  transcription factor p65 isoform X1

    UniProtKB/TrEMBL
    H0VZS0
    Related
    ENSCPOP00000016204.2
    Conserved Domains (2) summary
    cd07885
    Location:19 → 187
    RHD-n_RelA; N-terminal sub-domain of the Rel homology domain (RHD) of RelA
    cd01177
    Location:194 → 290
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...

  3. XM_013150773.2 → XP_013006227.1  transcription factor p65 isoform X2

    UniProtKB/TrEMBL
    A0A286XZ59
    Related
    ENSCPOP00000030595.1
    Conserved Domains (2) summary
    cd07885
    Location:10 → 178
    RHD-n_RelA; N-terminal sub-domain of the Rel homology domain (RHD) of RelA
    cd01177
    Location:185 → 281
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...

  4. XM_063227534.1 → XP_063083604.1  transcription factor p65 isoform X3

Nucleotide Protein
Heading Accession and Version

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Molecular Biology Databases
Research Materials