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Chrne cholinergic receptor nicotinic epsilon subunit [ Cavia porcellus (domestic guinea pig) ]

Gene ID: 100722702, updated on 8-Mar-2024

Summary

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Gene symbol
Chrne
Gene description
cholinergic receptor nicotinic epsilon subunit
See related
Ensembl:ENSCPOG00000024620
Gene type
protein coding
RefSeq status
MODEL
Organism
Cavia porcellus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Orthologs
human mouse all
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Genomic context

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See Chrne in Genome Data Viewer
Location:
chromosome: Un
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947515.1 (35995495..36020568)
103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176358.1 (9985708..9990896, complement)

NW_026947515.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 167 Neighboring gene solute carrier family 25 member 11 Neighboring gene glycoprotein Ib platelet subunit alpha Neighboring gene chromosome unknown C17orf107 homolog Neighboring gene misshapen like kinase 1 Neighboring gene phospholipase D2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables acetylcholine-gated monoatomic cation-selective channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
acetylcholine receptor subunit epsilon
Names
cholinergic receptor, nicotinic, epsilon polypeptide

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

  1. NW_026947515.1 Reference mCavPor4.1

    Range
    35995495..36020568
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063241772.1 → XP_063097842.1  acetylcholine receptor subunit epsilon isoform X2

  2. XM_063241775.1 → XP_063097845.1  acetylcholine receptor subunit epsilon isoform X5

  3. XM_063241767.1 → XP_063097837.1  acetylcholine receptor subunit epsilon isoform X1

  4. XM_063241768.1 → XP_063097838.1  acetylcholine receptor subunit epsilon isoform X2

  5. XM_063241769.1 → XP_063097839.1  acetylcholine receptor subunit epsilon isoform X2

  6. XM_063241771.1 → XP_063097841.1  acetylcholine receptor subunit epsilon isoform X2

  7. XM_063241770.1 → XP_063097840.1  acetylcholine receptor subunit epsilon isoform X2

  8. XM_063241779.1 → XP_063097849.1  acetylcholine receptor subunit epsilon isoform X12

  9. XM_063241774.1 → XP_063097844.1  acetylcholine receptor subunit epsilon isoform X5

  10. XM_063241773.1 → XP_063097843.1  acetylcholine receptor subunit epsilon isoform X4

  11. XM_023563564.2 → XP_023419332.1  acetylcholine receptor subunit epsilon isoform X6

    Conserved Domains (2) summary
    pfam02931
    Location:24 → 166
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:451 → 606
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

  12. XM_023563565.2 → XP_023419333.1  acetylcholine receptor subunit epsilon isoform X7

    Conserved Domains (1) summary
    pfam02931
    Location:24 → 166
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain

  13. XM_063241765.1 → XP_063097835.1  acetylcholine receptor subunit epsilon isoform X1

  14. XM_063241766.1 → XP_063097836.1  acetylcholine receptor subunit epsilon isoform X1

  15. XM_023563562.2 → XP_023419330.1  acetylcholine receptor subunit epsilon isoform X1

    Conserved Domains (3) summary
    pfam02931
    Location:24 → 166
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:452 → 666
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
    cl26464
    Location:271 → 433
    Atrophin-1; Atrophin-1 family

  16. XM_023563567.2 → XP_023419335.1  acetylcholine receptor subunit epsilon isoform X11

    Conserved Domains (1) summary
    pfam02931
    Location:24 → 166
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain

  17. XM_063241777.1 → XP_063097847.1  acetylcholine receptor subunit epsilon isoform X9

  18. XM_023563563.2 → XP_023419331.1  acetylcholine receptor subunit epsilon isoform X3

    Conserved Domains (3) summary
    pfam02931
    Location:24 → 166
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:452 → 679
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
    pfam15822
    Location:289 → 411
    MISS; MAPK-interacting and spindle-stabilizing protein-like

  19. XM_023563566.2 → XP_023419334.1  acetylcholine receptor subunit epsilon isoform X8

    Conserved Domains (2) summary
    pfam02931
    Location:24 → 200
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:398 → 553
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

  20. XM_063241778.1 → XP_063097848.1  acetylcholine receptor subunit epsilon isoform X10

  21. XM_013148787.3 → XP_013004241.1  acetylcholine receptor subunit epsilon isoform X13

    See identical proteins and their annotated locations for XP_013004241.1

    Conserved Domains (2) summary
    pfam02931
    Location:24 → 240
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:247 → 461
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

  22. XM_003466289.4 → XP_003466337.1  acetylcholine receptor subunit epsilon isoform X14

    UniProtKB/TrEMBL
    H0W8Y5
    Related
    ENSCPOP00000019443.1
    Conserved Domains (3) summary
    TIGR00860
    Location:20 → 475
    LIC; Cation transporter family protein
    pfam02931
    Location:24 → 240
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:247 → 474
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

RNA

  1. XR_001200479.2 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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