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Cav1 caveolin 1 [ Cavia porcellus (domestic guinea pig) ]

Gene ID: 100718512, updated on 8-Mar-2024

Summary

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Gene symbol
Cav1
Gene description
caveolin 1
See related
Ensembl:ENSCPOG00000002524
Gene type
protein coding
RefSeq status
MODEL
Organism
Cavia porcellus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Orthologs
human mouse all
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Genomic context

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See Cav1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947485.1 (50973844..51007031, complement)
103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176408.1 (37940217..37973386)

NW_026947485.1Genomic Context describing neighboring genes Neighboring gene capping actin protein of muscle Z-line subunit alpha 2 Neighboring gene MET proto-oncogene, receptor tyrosine kinase Neighboring gene uncharacterized LOC111758392 Neighboring gene caveolin 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The association between CDC42 and caveolin-1 is involved in the regulation of capacitation and acrosome reaction of guinea pig and mouse sperm. Baltiérrez-Hoyos R, et al. Reproduction, 2012 Jul. PMID 22596063
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables molecular adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane transporter binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in caveola assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of endothelial cell proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cytosolic calcium ion concentration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in caveola IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in sarcolemma IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
caveolin-1
Names
caveolin 1, caveolae protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

  1. NW_026947485.1 Reference mCavPor4.1

    Range
    50973844..51007031 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003475136.5 → XP_003475184.1  caveolin-1 isoform X1

    See identical proteins and their annotated locations for XP_003475184.1

    UniProtKB/TrEMBL
    H0W1D1, Q07E12
    Related
    ENSCPOP00000027566.1
    Conserved Domains (1) summary
    pfam01146
    Location:43 → 175
    Caveolin; Caveolin

  2. XM_005006048.4 → XP_005006105.1  caveolin-1 isoform X2

    See identical proteins and their annotated locations for XP_005006105.1

    UniProtKB/TrEMBL
    H0W1D1
    Conserved Domains (1) summary
    pfam01146
    Location:12 → 144
    Caveolin; Caveolin
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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