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Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 [ Cavia porcellus (domestic guinea pig) ]

Gene ID: 100716179, updated on 8-Mar-2024

Summary

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Gene symbol
Map4k3
Gene description
mitogen-activated protein kinase kinase kinase kinase 3
See related
Ensembl:ENSCPOG00000012852
Gene type
protein coding
RefSeq status
MODEL
Organism
Cavia porcellus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Orthologs
human mouse all
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Genomic context

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See Map4k3 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
35
Annotation release Status Assembly Chr Location
RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947484.1 (219046653..219220669)
103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176401.1 (23732623..23906380, complement)

NW_026947484.1Genomic Context describing neighboring genes Neighboring gene THUMP domain containing 2 Neighboring gene transmembrane protein 178A Neighboring gene uncharacterized LOC134478169 Neighboring gene non-histone chromosomal protein HMG-14-like Neighboring gene large ribosomal subunit protein uL22-like Neighboring gene cyclin dependent kinase like 4 Neighboring gene uncharacterized LOC134471278

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables MAP kinase kinase kinase kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mitogen-activated protein kinase kinase kinase kinase 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

  1. NW_026947484.1 Reference mCavPor4.1

    Range
    219046653..219220669
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003473045.5 → XP_003473093.1  mitogen-activated protein kinase kinase kinase kinase 3 isoform X1

    UniProtKB/TrEMBL
    H0VME1
    Related
    ENSCPOP00000011569.3
    Conserved Domains (3) summary
    smart00036
    Location:561 → 874
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:16 → 273
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06613
    Location:15 → 273
    STKc_MAP4K3_like; Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase (MAP4K) 3-like Serine/Threonine Kinases

  2. XM_005005056.4 → XP_005005113.1  mitogen-activated protein kinase kinase kinase kinase 3 isoform X2

    Conserved Domains (3) summary
    smart00036
    Location:543 → 856
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:16 → 273
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06613
    Location:15 → 273
    STKc_MAP4K3_like; Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase (MAP4K) 3-like Serine/Threonine Kinases

  3. XM_003473046.5 → XP_003473094.1  mitogen-activated protein kinase kinase kinase kinase 3 isoform X3

    UniProtKB/TrEMBL
    A0A286X8S0
    Related
    ENSCPOP00000021822.1
    Conserved Domains (3) summary
    smart00036
    Location:540 → 853
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:16 → 273
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06613
    Location:15 → 273
    STKc_MAP4K3_like; Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase (MAP4K) 3-like Serine/Threonine Kinases

  4. XM_063229415.1 → XP_063085485.1  mitogen-activated protein kinase kinase kinase kinase 3 isoform X4

  5. XM_023566361.2 → XP_023422129.1  mitogen-activated protein kinase kinase kinase kinase 3 isoform X5

    Conserved Domains (2) summary
    smart00036
    Location:498 → 811
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06613
    Location:1 → 210
    STKc_MAP4K3_like; Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase (MAP4K) 3-like Serine/Threonine Kinases

  6. XM_063229427.1 → XP_063085497.1  mitogen-activated protein kinase kinase kinase kinase 3 isoform X6

RNA

  1. XR_010040553.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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