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Dhx58 DExH-box helicase 58 [ Cavia porcellus (domestic guinea pig) ]

Gene ID: 100715966, updated on 8-Mar-2024

Summary

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Gene symbol
Dhx58
Gene description
DExH-box helicase 58
See related
Ensembl:ENSCPOG00000023721
Gene type
protein coding
RefSeq status
MODEL
Organism
Cavia porcellus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Orthologs
human mouse all
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Genomic context

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See Dhx58 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947489.1 (94171638..94177131, complement)
103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176366.1 (12060165..12065667, complement)

NW_026947489.1Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member C7 Neighboring gene NFKB inhibitor interacting Ras like 2 Neighboring gene zinc finger protein 385C Neighboring gene lysine acetyltransferase 2A Neighboring gene heat shock protein family B (small) member 9

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in antiviral innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytoplasmic pattern recognition receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of RIG-I signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ATP-dependent RNA helicase DHX58

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

  1. NW_026947489.1 Reference mCavPor4.1

    Range
    94171638..94177131 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013149677.3 → XP_013005131.1  ATP-dependent RNA helicase DHX58 isoform X1

    UniProtKB/TrEMBL
    H0VVQ1
    Related
    ENSCPOP00000014777.1
    Conserved Domains (5) summary
    COG1111
    Location:2 → 506
    MPH1; ERCC4-related helicase [Replication, recombination and repair]
    cd15806
    Location:552 → 664
    LGP2_C; C-terminal domain of Laboratory of Genetics and Physiology 2 (LGP2), a cytoplasmic viral RNA receptor
    cd12090
    Location:227 → 345
    MDA5_ID; Insert domain of MDA5
    pfam00271
    Location:350 → 472
    Helicase_C; Helicase conserved C-terminal domain
    pfam04851
    Location:1 → 170
    ResIII; Type III restriction enzyme, res subunit

  2. XM_063251560.1 → XP_063107630.1  ATP-dependent RNA helicase DHX58 isoform X2

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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