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TOP2B DNA topoisomerase II beta [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100668841, updated on 11-Apr-2024

Summary

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Gene symbol
TOP2B
Gene description
DNA topoisomerase II beta
See related
EnsemblRapid:ENSLAFG00000015837
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human mouse all
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Genomic context

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See TOP2B in Genome Data Viewer
Location:
chromosome: 27
Exon count:
36
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 27 NC_087368.1 (24995599..25067882, complement)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573456.1 (13803748..13876159)

Chromosome 27 - NC_087368.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC135228763 Neighboring gene ATP-dependent RNA helicase DHX8-like Neighboring gene N-glycanase 1 Neighboring gene 3-oxoacyl-ACP synthase, mitochondrial

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA topological change IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in resolution of meiotic recombination intermediates IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sister chromatid segregation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA topoisomerase 2-beta
Names
topoisomerase (DNA) II beta

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087368.1 Reference mLoxAfr1.hap2

    Range
    24995599..25067882 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_064277403.1 → XP_064133473.1  DNA topoisomerase 2-beta isoform X2

    Related
    ENSLAFP00000013292.4, ENSLAFT00000015847.4

  2. XM_064277402.1 → XP_064133472.1  DNA topoisomerase 2-beta isoform X1

    Related
    ENSLAFP00000048507.1, ENSLAFT00000039894.1
Nucleotide Protein
Heading Accession and Version

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