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FLT3 fms related receptor tyrosine kinase 3 [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100668366, updated on 11-Apr-2024

Summary

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Gene symbol
FLT3
Gene description
fms related receptor tyrosine kinase 3
See related
EnsemblRapid:ENSLAFG00000015599
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human mouse all
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Genomic context

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See FLT3 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
31
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 23 NC_087364.1 (19461239..19584483)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573449.1 (14018156..14126174, complement)

Chromosome 23 - NC_087364.1Genomic Context describing neighboring genes Neighboring gene poly(A) specific ribonuclease subunit PAN3 Neighboring gene uncharacterized LOC135228562 Neighboring gene ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase Neighboring gene caudal type homeobox 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in B cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
receptor-type tyrosine-protein kinase FLT3
Names
fms related tyrosine kinase 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087364.1 Reference mLoxAfr1.hap2

    Range
    19461239..19584483
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_064275309.1 → XP_064131379.1  receptor-type tyrosine-protein kinase FLT3 isoform X5

  2. XM_064275306.1 → XP_064131376.1  receptor-type tyrosine-protein kinase FLT3 isoform X3

    Related
    ENSLAFP00000022768.2, ENSLAFT00000028503.2

  3. XM_064275308.1 → XP_064131378.1  receptor-type tyrosine-protein kinase FLT3 isoform X5

  4. XM_064275303.1 → XP_064131373.1  receptor-type tyrosine-protein kinase FLT3 isoform X1

  5. XM_064275304.1 → XP_064131374.1  receptor-type tyrosine-protein kinase FLT3 isoform X1

  6. XM_064275305.1 → XP_064131375.1  receptor-type tyrosine-protein kinase FLT3 isoform X2

    Related
    ENSLAFP00000039060.1, ENSLAFT00000046240.1

  7. XM_064275307.1 → XP_064131377.1  receptor-type tyrosine-protein kinase FLT3 isoform X4

    Related
    ENSLAFP00000013080.5, ENSLAFT00000015605.5

  8. XM_064275313.1 → XP_064131383.1  receptor-type tyrosine-protein kinase FLT3 isoform X7

  9. XM_064275311.1 → XP_064131381.1  receptor-type tyrosine-protein kinase FLT3 isoform X7

  10. XM_064275310.1 → XP_064131380.1  receptor-type tyrosine-protein kinase FLT3 isoform X6

Nucleotide Protein
Heading Accession and Version

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