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HMGCL 3-hydroxy-3-methylglutaryl-CoA lyase [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100667236, updated on 11-Apr-2024

Summary

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Gene symbol
HMGCL
Gene description
3-hydroxy-3-methylglutaryl-CoA lyase
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human mouse all
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Genomic context

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See HMGCL in Genome Data Viewer
Location:
chromosome: 3
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 3 NC_087344.1 (59006305..59023164, complement)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573454.1 (1898708..1915529, complement)

Chromosome 3 - NC_087344.1Genomic Context describing neighboring genes Neighboring gene PITH domain containing 1 Neighboring gene UDP-galactose-4-epimerase Neighboring gene lysophospholipase 2 Neighboring gene alpha-L-fucosidase 1 Neighboring gene cannabinoid receptor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA lyase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-leucine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ketone body biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxymethylglutaryl-CoA lyase, mitochondrial
Names
3-hydroxymethyl-3-methylglutaryl-CoA lyase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087344.1 Reference mLoxAfr1.hap2

    Range
    59006305..59023164 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023554356.2 → XP_023410124.1  hydroxymethylglutaryl-CoA lyase, mitochondrial

    UniProtKB/TrEMBL
    G3TIP1
    Conserved Domains (1) summary
    PLN02746
    Location:11 → 262
    PLN02746; hydroxymethylglutaryl-CoA lyase
Nucleotide Protein
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