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PTEN phosphatase and tensin homolog [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100660561, updated on 11-Apr-2024

Summary

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Gene symbol
PTEN
Gene description
phosphatase and tensin homolog
See related
EnsemblRapid:ENSLAFG00000005292
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human mouse all
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Genomic context

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See PTEN in Genome Data Viewer
Location:
chromosome: 16
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 16 NC_087357.1 (47267346..47372770, complement)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573430.1 (31012489..31118386, complement)

Chromosome 16 - NC_087357.1Genomic Context describing neighboring genes Neighboring gene renalase, FAD dependent amine oxidase Neighboring gene uncharacterized LOC135227921 Neighboring gene mediator of RNA polymerase II transcription subunit 6-like Neighboring gene uncharacterized LOC135227922 Neighboring gene uncharacterized LOC111750312 Neighboring gene killin, p53 regulated DNA replication inhibitor Neighboring gene ATPase family AAA domain containing 1 Neighboring gene 3'-phosphoadenosine 5'-phosphosulfate synthase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell motility IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087357.1 Reference mLoxAfr1.hap2

    Range
    47267346..47372770 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_064269603.1 → XP_064125673.1  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1

    Related
    ENSLAFP00000004434.4, ENSLAFT00000005293.4

  2. XM_064269604.1 → XP_064125674.1  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X2

  3. XM_064269605.1 → XP_064125675.1  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X2

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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