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PDHX pyruvate dehydrogenase complex component X [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100660107, updated on 11-Apr-2024

Summary

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Gene symbol
PDHX
Gene description
pyruvate dehydrogenase complex component X
See related
EnsemblRapid:ENSLAFG00000013165
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human mouse all
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Genomic context

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See PDHX in Genome Data Viewer
Location:
chromosome: 7
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 7 NC_087348.1 (48171722..48258896, complement)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573441.1 (14616092..14696871, complement)

Chromosome 7 - NC_087348.1Genomic Context describing neighboring genes Neighboring gene peptidase domain containing associated with muscle regeneration 1 Neighboring gene solute carrier family 1 member 2 Neighboring gene CD44 molecule (IN blood group) Neighboring gene U1 spliceosomal RNA Neighboring gene APAF1 interacting protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA biosynthetic process from pyruvate IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of pyruvate dehydrogenase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pyruvate dehydrogenase protein X component, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087348.1 Reference mLoxAfr1.hap2

    Range
    48171722..48258896 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_064288305.1 → XP_064144375.1  pyruvate dehydrogenase protein X component, mitochondrial isoform X1

    Related
    ENSLAFP00000021474.2, ENSLAFT00000029709.2

  2. XM_003412281.4 → XP_003412329.1  pyruvate dehydrogenase protein X component, mitochondrial isoform X2

    UniProtKB/TrEMBL
    G3TAT9
    Related
    ENSLAFP00000011019.3, ENSLAFT00000013167.4
    Conserved Domains (4) summary
    cd06849
    Location:63 → 137
    lipoyl_domain; Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid ...
    TIGR01349
    Location:65 → 506
    PDHac_trf_mito; pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form
    pfam00198
    Location:297 → 506
    2-oxoacid_dh; 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
    pfam02817
    Location:189 → 221
    E3_binding; e3 binding domain

RNA

  1. XR_010322445.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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