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DBT dihydrolipoamide branched chain transacylase E2 [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100658104, updated on 11-Apr-2024

Summary

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Gene symbol
DBT
Gene description
dihydrolipoamide branched chain transacylase E2
See related
EnsemblRapid:ENSLAFG00000006373
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human mouse all
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Genomic context

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See DBT in Genome Data Viewer
Location:
chromosome: 3
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 3 NC_087344.1 (178250534..178332385)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573431.1 (43914812..43994829, complement)

Chromosome 3 - NC_087344.1Genomic Context describing neighboring genes Neighboring gene cell division cycle 14A Neighboring gene RNA 3'-terminal phosphate cyclase Neighboring gene leucine rich repeat containing 39 Neighboring gene tRNA methyltransferase 13 homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables lipoic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087344.1 Reference mLoxAfr1.hap2

    Range
    178250534..178332385
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023547413.2 → XP_023403181.1  lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform X2

    Related
    ENSLAFP00000005355.4, ENSLAFT00000006375.4
    Conserved Domains (1) summary
    cl27351
    Location:67 → 428
    E3_binding; e3 binding domain

  2. XM_010589507.3 → XP_010587809.1  lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform X1

    UniProtKB/TrEMBL
    G3SY24
    Related
    ENSLAFP00000031411.1, ENSLAFT00000052375.1
    Conserved Domains (4) summary
    cd06849
    Location:65 → 138
    lipoyl_domain; Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid ...
    PLN02528
    Location:67 → 482
    PLN02528; 2-oxoisovalerate dehydrogenase E2 component
    pfam00198
    Location:267 → 479
    2-oxoacid_dh; 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
    pfam02817
    Location:172 → 205
    E3_binding; e3 binding domain

  3. XM_064282491.1 → XP_064138561.1  lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform X3

Nucleotide Protein
Heading Accession and Version

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