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SPTLC1 serine palmitoyltransferase long chain base subunit 1 [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100657962, updated on 11-Apr-2024

Summary

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Gene symbol
SPTLC1
Gene description
serine palmitoyltransferase long chain base subunit 1
See related
EnsemblRapid:ENSLAFG00000011897
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human mouse all
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Genomic context

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See SPTLC1 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 9 NC_087350.1 (9442973..9516325, complement)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573507.1 (3780605..3853795, complement)

Chromosome 9 - NC_087350.1Genomic Context describing neighboring genes Neighboring gene nuclear factor, interleukin 3 regulated Neighboring gene receptor tyrosine kinase like orphan receptor 2 Neighboring gene uncharacterized LOC135232363 Neighboring gene spermatogenesis-associated protein 31A6-like Neighboring gene contactin associated protein family member 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine C-palmitoyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphingosine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine palmitoyltransferase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087350.1 Reference mLoxAfr1.hap2

    Range
    9442973..9516325 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003420433.4 → XP_003420481.1  serine palmitoyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    G3T8D8
    Related
    ENSLAFP00000041899.1, ENSLAFT00000061392.1
    Conserved Domains (2) summary
    pfam00155
    Location:98 → 448
    Aminotran_1_2; Aminotransferase class I and II
    cl18945
    Location:11 → 448
    AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...

  2. XM_064291043.1 → XP_064147113.1  serine palmitoyltransferase 1 isoform X2

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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