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RECQL RecQ like helicase [ Sus scrofa (pig) ]

Gene ID: 100621847, updated on 17-Aug-2024

Summary

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Official Symbol
RECQLprovided by VGNC
Official Full Name
RecQ like helicaseprovided by VGNC
Primary source
VGNC:VGNC:92195
See related
Ensembl:ENSSSCG00000000580
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Ubiquitous expression in spleen (RPKM 8.1), lung (RPKM 6.6) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See RECQL in Genome Data Viewer
Location:
chromosome: 5
Exon count:
16
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 5 NC_010447.5 (51953460..51995619)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 5 NC_010447.4 (55229615..55272155)

Chromosome 5 - NC_010447.5Genomic Context describing neighboring genes Neighboring gene spexin hormone Neighboring gene golgi transport 1B Neighboring gene pyridine nucleotide-disulphide oxidoreductase domain 1 Neighboring gene solute carrier organic anion transporter family member 1A2 Neighboring gene islet amyloid polypeptide Neighboring gene solute carrier organic anion transporter family member 1B2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3'-5' DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables four-way junction helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA unwinding involved in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ATP-dependent DNA helicase Q1
Names
RecQ protein-like (DNA helicase Q1-like)
NP_001240636.1
XP_020946751.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001253707.1 → NP_001240636.1  ATP-dependent DNA helicase Q1

    Status: VALIDATED

    Source sequence(s)
    AK344949
    UniProtKB/TrEMBL
    A0A287BGJ9, A0A8D1CNG3
    Related
    ENSSSCP00000055660.1, ENSSSCT00000059872.3
    Conserved Domains (5) summary
    TIGR00614
    Location:82 → 543
    recQ_fam; ATP-dependent DNA helicase, RecQ family
    cd00079
    Location:285 → 417
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00270
    Location:93 → 259
    DEAD; DEAD/DEAH box helicase
    pfam16124
    Location:422 → 478
    RecQ_Zn_bind; RecQ zinc-binding
    cl09632
    Location:484 → 586
    RQC; RQC domain

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010447.5 Reference Sscrofa11.1 Primary Assembly

    Range
    51953460..51995619
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021091092.1 → XP_020946751.1  ATP-dependent DNA helicase Q1 isoform X1

    UniProtKB/TrEMBL
    A0A287BGJ9, A0A8D1CNG3
    Conserved Domains (1) summary
    cl26939
    Location:1 → 440
    DEXDc; DEAD-like helicases superfamily
Nucleotide Protein
Heading Accession and Version

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