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PFKL phosphofructokinase, liver type [ Sus scrofa (pig) ]

Gene ID: 100621757, updated on 17-Aug-2024

Summary

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Official Symbol
PFKLprovided by VGNC
Official Full Name
phosphofructokinase, liver typeprovided by VGNC
Primary source
VGNC:VGNC:91337
See related
Ensembl:ENSSSCG00000028197
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Ubiquitous expression in heart (RPKM 27.9), kidney (RPKM 26.4) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See PFKL in Genome Data Viewer
Location:
chromosome: 13
Exon count:
22
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 13 NC_010455.5 (207167287..207191688)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 13 NC_010455.4 (217047266..217071450)

Chromosome 13 - NC_010455.5Genomic Context describing neighboring genes Neighboring gene DNA methyltransferase 3 like Neighboring gene autoimmune regulator Neighboring gene cilia and flagella associated protein 410 Neighboring gene uncharacterized LOC102158266

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructokinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables AMP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-6-phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables identical protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables monosaccharide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical glycolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose 1,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose 6-phosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of 6-phosphofructokinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ATP-dependent 6-phosphofructokinase, liver type

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010455.5 Reference Sscrofa11.1 Primary Assembly

    Range
    207167287..207191688
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021071510.1 → XP_020927169.1  ATP-dependent 6-phosphofructokinase, liver type

    UniProtKB/TrEMBL
    A0A480K104, A0A480UKG5, A0A8D1L9X8, I3LFQ5
    Related
    ENSSSCP00000022897.3, ENSSSCT00000025356.3
    Conserved Domains (1) summary
    cd00764
    Location:13 → 773
    Eukaryotic_PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent ...

RNA

  1. XR_002338189.1 RNA Sequence

    Related
    ENSSSCT00000042856.3
Nucleotide Protein
Heading Accession and Version

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