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ACHE acetylcholinesterase [ Sus scrofa (pig) ]

Gene ID: 100621099, updated on 17-Aug-2024

Summary

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Official Symbol
ACHEprovided by VGNC
Official Full Name
acetylcholinesteraseprovided by VGNC
Primary source
VGNC:VGNC:97029
See related
Ensembl:ENSSSCG00000030303
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Low expression observed in reference dataset See more
Orthologs
human mouse all
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Genomic context

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See ACHE in Genome Data Viewer
Location:
chromosome: 3
Exon count:
6
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 3 NC_010445.4 (8732451..8738274, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 3 NC_010445.3 (8159377..8165197, complement)

Chromosome 3 - NC_010445.4Genomic Context describing neighboring genes Neighboring gene serrate, RNA effector molecule Neighboring gene UFM1 specific peptidase 1 Neighboring gene uncharacterized LOC110259881 Neighboring gene mucin-3B-like Neighboring gene elastin-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Reactivation of sarin-inhibited pig brain acetylcholinesterase using oxime antidotes. Kuca K, et al. J Med Toxicol, 2006 Dec. PMID 18072133, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Compared potency of oxime antidotes to reactivate pig brain acetylcholinesterase (AChE) after sarin exposure.
    Title: Reactivation of sarin-inhibited pig brain acetylcholinesterase using oxime antidotes.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables acetylcholinesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetylcholine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in choline metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
acetylcholinesterase
Names
acetylcholinesterase (Cartwright blood group)
acetylcholinesterase (Yt blood group)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010445.4 Reference Sscrofa11.1 Primary Assembly

    Range
    8732451..8738274 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003354481.4 → XP_003354529.1  acetylcholinesterase isoform X3

    UniProtKB/TrEMBL
    A0A4X1UH96
    Related
    ENSSSCP00000042816.2, ENSSSCT00000058868.3
    Conserved Domains (2) summary
    pfam08674
    Location:577 → 610
    AChE_tetra; Acetylcholinesterase tetramerisation domain
    pfam00135
    Location:36 → 562
    COesterase; Carboxylesterase family

  2. XM_021086251.1 → XP_020941910.1  acetylcholinesterase isoform X3

    UniProtKB/TrEMBL
    A0A4X1UH96
    Conserved Domains (2) summary
    pfam08674
    Location:577 → 610
    AChE_tetra; Acetylcholinesterase tetramerisation domain
    pfam00135
    Location:36 → 562
    COesterase; Carboxylesterase family

  3. XM_013995487.2 → XP_013850941.2  acetylcholinesterase isoform X1

    UniProtKB/TrEMBL
    A0A480ZGK1, A0A8D1NQW2
    Conserved Domains (2) summary
    pfam08674
    Location:730 → 763
    AChE_tetra; Acetylcholinesterase tetramerisation domain
    pfam00135
    Location:189 → 715
    COesterase; Carboxylesterase family

  4. XM_013995488.2 → XP_013850942.2  acetylcholinesterase isoform X2

    UniProtKB/TrEMBL
    A0A5G2QVL5, A0A8D0LJY4
    Related
    ENSSSCP00000065978.1, ENSSSCT00000090230.2
    Conserved Domains (1) summary
    pfam00135
    Location:189 → 715
    COesterase; Carboxylesterase family
Nucleotide Protein
Heading Accession and Version

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