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MIR4644 microRNA 4644 [ Homo sapiens (human) ]

Gene ID: 100616430, updated on 17-Jun-2024

Summary

Official Symbol
MIR4644provided by HGNC
Official Full Name
microRNA 4644provided by HGNC
Primary source
HGNC:HGNC:41687
See related
Ensembl:ENSG00000266245 miRBase:MI0017271; AllianceGenome:HGNC:41687
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

See MIR4644 in Genome Data Viewer
Location:
6q27
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (170330761..170330844)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (171689448..171689531)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (170639849..170639932)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC285804 Neighboring gene long intergenic non-protein coding RNA 1624 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr6:170591232-170592431 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr6:170604755-170605382 Neighboring gene delta like canonical Notch ligand 1 Neighboring gene family with sequence similarity 120 member B Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_91390 Neighboring gene NANOG hESC enhancer GRCh37_chr6:170664768-170665298 Neighboring gene uncharacterized LOC124901474 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr6:170695897-170697096 Neighboring gene uncharacterized LOC124901475

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_039787.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AL078605
    Related
    ENST00000579929.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    170330761..170330844
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187553.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    57999..58082
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    171689448..171689531
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)