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MIR4799 microRNA 4799 [ Homo sapiens (human) ]

Gene ID: 100616246, updated on 10-Oct-2023

Summary

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Official Symbol
MIR4799provided by HGNC
Official Full Name
microRNA 4799provided by HGNC
Primary source
HGNC:HGNC:41584
See related
Ensembl:ENSG00000264274 miRBase:MI0017446; AllianceGenome:HGNC:41584
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

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See MIR4799 in Genome Data Viewer
Location:
4q31.23
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (147782595..147782668)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (151106687..151106760)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (148703746..148703819)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene NANOG hESC enhancer GRCh37_chr4:148576650-148577308 Neighboring gene protein arginine methyltransferase 9 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:148619575-148620075 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22003 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:148652850-148653742 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:148653743-148654635 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22005 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:148659209-148659934 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22006 Neighboring gene Rho GTPase activating protein 10 Neighboring gene RNA, 5S ribosomal pseudogene 165 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22007 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22008 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22009 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22010 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:148741752-148742252 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:148742253-148742753 Neighboring gene RNA, 7SL, cytoplasmic 254, pseudogene Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr4:148752558-148753757 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22011 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:148787949-148788626 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:148788627-148789303 Neighboring gene ret finger protein like 4A pseudogene 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. Persson H, et al. Cancer Res, 2011 Jan 1. PMID 21199797
  2. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Other Names

  • hsa-mir-4799

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_039962.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC093835
    Related
    ENST00000578951.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    147782595..147782668
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    151106687..151106760
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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