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MIR4633 microRNA 4633 [ Homo sapiens (human) ]

Gene ID: 100616175, updated on 17-Sep-2024

Summary

Official Symbol
MIR4633provided by HGNC
Official Full Name
microRNA 4633provided by HGNC
Primary source
HGNC:HGNC:41822
See related
Ensembl:ENSG00000264563 miRBase:MI0017260; AllianceGenome:HGNC:41822
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

See MIR4633 in Genome Data Viewer
Location:
5q23.3
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (129097688..129097766)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (129616386..129616464)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (128433381..128433459)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102723638 Neighboring gene uncharacterized LOC124901060 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16298 Neighboring gene isochorismatase domain containing 1 Neighboring gene uncharacterized LOC102723654 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:128499979-128500478 Neighboring gene uncharacterized LOC105379169 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_80935 Neighboring gene microRNA 4460

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_039776.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC008679
    Related
    ENST00000584064.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    129097688..129097766
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    129616386..129616464
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)