U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MIR4697 microRNA 4697 [ Homo sapiens (human) ]

Gene ID: 100616119, updated on 17-Sep-2024

Summary

Official Symbol
MIR4697provided by HGNC
Official Full Name
microRNA 4697provided by HGNC
Primary source
HGNC:HGNC:41570
See related
Ensembl:ENSG00000284020 miRBase:MI0017330; AllianceGenome:HGNC:41570
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See MIR4697 in Genome Data Viewer
Location:
11q25
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (133898504..133898581, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (133940798..133940875, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (133768399..133768476, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133712096-133712638 Neighboring gene spermatogenesis associated 19 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr11:133724195-133725394 Neighboring gene calponin 2 pseudogene Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133764343-133765238 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133765239-133766134 Neighboring gene immunoglobulin superfamily member 9B Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4088 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133800389-133801061 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133804210-133804968 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133804969-133805727 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133809401-133810123 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133810124-133810845 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133814904-133815632 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133816362-133817090 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5767 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133821059-133821802 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133821803-133822546 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4089 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133863530-133864030 Neighboring gene long intergenic non-protein coding RNA 2730 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133890717-133891220 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133894031-133894833 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr11:133896267-133896838 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr11:133896839-133897409 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133901031-133901530 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133902231-133902958 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133902959-133903686 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133906753-133907724 Neighboring gene long intergenic non-protein coding RNA 2731

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

EBI GWAS Catalog

Description
Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.
EBI GWAS Catalog

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_039846.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AP001979
    Related
    ENST00000582977.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    133898504..133898581 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    133940798..133940875 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)